Srd5a3 (NM_001013990) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR206628L4V

Lenti ORF particles, Srd5a3 (GFP-tagged ORF) - Rat steroid 5 alpha-reductase 3 (Srd5a3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Srd5a3
• Synonyms: RGD1308828; S5AR 3
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001013990
• ORF Size: 834 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR206628).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001013990.1, NP_001014012.1
• RefSeq Size: 1370 bp
• RefSeq ORF: 837 bp
• Locus ID: 305291
• UniProt ID: Q5RJM1
• Cytogenetics: 14p11
• Gene Summary: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).[UniProtKB/Swiss-Prot Function]