Tnfaip1 (NM_182950) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR204308L3V

Lenti ORF particles, Tnfaip1 (Myc-DDK-tagged ORF) - Rat tumor necrosis factor, alpha-induced protein 1 (endothelial) (Tnfaip1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Tnfaip1
• Synonyms: Edp1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_182950
• ORF Size: 948 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR204308).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_182950.4, NP_891995.1
• RefSeq Size: 3885 bp
• RefSeq ORF: 951 bp
• Locus ID: 287543
• UniProt ID: Q7TNY1
• Cytogenetics: 10q25
• Gene Summary: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis (By similarity). May enhance the PCNA-dependent DNA polymerase delta activity.[UniProtKB/Swiss-Prot Function]