ICEBERG (CARD18) (NM_021571) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC224896L4V

Lenti ORF particles, CARD18 (mGFP-tagged) - Human caspase recruitment domain family, member 18 (CARD18), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: ICEBERG
• Synonyms: ICEBERG; pseudo-ICE; UNQ5804
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_021571
• ORF Size: 270 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224896).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021571.2
• RefSeq Size: 431 bp
• RefSeq ORF: 273 bp
• Locus ID: 59082
• UniProt ID: P57730
• Cytogenetics: 11q22.3
• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway
• MW: 10 kDa
• Gene Summary: Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.[UniProtKB/Swiss-Prot Function]