RABEP1 (NM_001083585) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC224499L3V

Lenti ORF particles, RABEP1 (Myc-DDK-tagged)-Human rabaptin, RAB GTPase binding effector protein 1 (RABEP1), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: RABEP1
• Synonyms: RAB5EP; RABPT5
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001083585
• ORF Size: 2487 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224499).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001083585.1
• RefSeq Size: 5322 bp
• RefSeq ORF: 2490 bp
• Locus ID: 9135
• UniProt ID: Q15276
• Cytogenetics: 17p13.2
• Protein Pathways: Endocytosis
• MW: 95.3 kDa
• Gene Summary: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity).[UniProtKB/Swiss-Prot Function]