Bcl 7A (BCL7A) (NM_020993) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223737L4V

Lenti ORF particles, BCL7A (mGFP-tagged)-Human B-cell CLL/lymphoma 7A (BCL7A), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Bcl 7A
• Synonyms: BCL7
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_020993
• ORF Size: 693 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223737).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020993.3, NP_066273.1
• RefSeq Size: 3714 bp
• RefSeq ORF: 696 bp
• Locus ID: 605
• UniProt ID: Q4VC05
• Cytogenetics: 12q24.31
• Domains: BCL_N
• Protein Families: Druggable Genome
• MW: 24.8 kDa
• Gene Summary: This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]