MCK10 (DDR1) (NM_013994) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC222819L4V
- LentiORF®
Lenti ORF particles, DDR1 (mGFP-tagged) - Human discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 3, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | MCK10 |
Synonyms | CAK; CD167; DDR; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_013994 |
ORF Size | 2757 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC222819).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_013994.2 |
RefSeq Size | 3678 bp |
RefSeq ORF | 2760 bp |
Locus ID | 780 |
UniProt ID | Q08345 |
Cytogenetics | 6p21.33 |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
MW | 101.8 kDa |
Gene Summary | Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |
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