CNGB1 (NM_001297) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220578L4V
- LentiORF®
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Lenti ORF particles, CNGB1 (mGFP-tagged)-Human cyclic nucleotide gated channel beta 1 (CNGB1), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | CNGB1 |
Synonyms | CNCG2; CNCG3L; CNCG4; CNG4; CNGB1B; GAR1; GARP; GARP2; RCNC2; RCNCb; RCNCbeta; RP45 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001297 |
ORF Size | 3753 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220578).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001297.4 |
RefSeq Size | 5663 bp |
RefSeq ORF | 3756 bp |
Locus ID | 1258 |
UniProt ID | Q14028 |
Cytogenetics | 16q21 |
Protein Families | Druggable Genome, Ion Channels: Cyclic nucleotide gated |
Protein Pathways | Olfactory transduction |
MW | 139.7 kDa |
Gene Summary | In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] |
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