SCRIBBLE (SCRIB) (NM_182706) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220211L3V
- LentiORF®
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Lenti ORF particles, SCRIB (Myc-DDK tagged) - Human scribbled homolog (Drosophila) (SCRIB), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | SCRIBBLE |
Synonyms | CRIB1; SCRB1; SCRIB1; Vartul |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_182706 |
ORF Size | 4965 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220211).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_182706.2 |
RefSeq Size | 5221 bp |
RefSeq ORF | 4968 bp |
Locus ID | 23513 |
UniProt ID | Q14160 |
Cytogenetics | 8q24.3 |
MW | 177.6 kDa |
Gene Summary | This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
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