CBX4 (NM_003655) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216414L2V

Lenti ORF particles, CBX4 (mGFP-tagged)-Human chromobox homolog 4 (CBX4), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CBX4
• Synonyms: NBP16; PC2
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003655
• ORF Size: 1680 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216414).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003655.2
• RefSeq Size: 2655 bp
• RefSeq ORF: 1683 bp
• Locus ID: 8535
• UniProt ID: O00257
• Cytogenetics: 17q25.3
• Domains: CHROMO
• Protein Families: Druggable Genome, Transcription Factors
• MW: 61.8 kDa
• Gene Summary: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I (PubMed:12679040). Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131 (PubMed:22825850).[UniProtKB/Swiss-Prot Function]