AKR7A2 (NM_003689) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC214673L3V
- LentiORF®
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Lenti ORF particles, AKR7A2 (Myc-DDK tagged) - Human aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | AKR7A2 |
Synonyms | AFAR; AFAR1; AFB1-AR1; AKR7 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_003689 |
ORF Size | 1077 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC214673).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003689.2 |
RefSeq Size | 1377 bp |
RefSeq ORF | 1080 bp |
Locus ID | 8574 |
UniProt ID | O43488 |
Cytogenetics | 1p36.13 |
Domains | aldo_ket_red |
Protein Families | Druggable Genome |
MW | 39.4 kDa |
Gene Summary | The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
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