DEDD (NM_001039712) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214260L4V

Lenti ORF particles, DEDD (mGFP-tagged) - Human death effector domain containing (DEDD), transcript variant 4, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: DEDD
• Synonyms: CASP8IP1; DEDD1; DEFT; FLDED1; KE05
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001039712
• ORF Size: 954 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214260).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001039712.1, NP_001034801.1
• RefSeq Size: 2300 bp
• RefSeq ORF: 957 bp
• Locus ID: 9191
• UniProt ID: O75618
• Cytogenetics: 1q23.3
• Protein Families: Druggable Genome, Transcription Factors
• MW: 36.8 kDa
• Gene Summary: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]