TRPM1 (NM_002420) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC213443L4V
- LentiORF®
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Lenti ORF particles, TRPM1 (mGFP-tagged) - Human transient receptor potential cation channel, subfamily M, member 1 (TRPM1), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | TRPM1 |
Synonyms | CSNB1C; LTRPC1; MLSN1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_002420 |
ORF Size | 4809 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC213443).
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OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002420.4 |
RefSeq Size | 5428 bp |
RefSeq ORF | 4812 bp |
Locus ID | 4308 |
UniProt ID | Q7Z4N2 |
Cytogenetics | 15q13.3 |
Domains | ion_trans |
Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
MW | 182 kDa |
Gene Summary | This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011] |
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