MITF (NM_198177) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC211586L2V
- LentiORF®
Lenti ORF particles, MITF (mGFP-tagged)-Human microphthalmia-associated transcription factor (MITF), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | MITF |
Synonyms | bHLHe32; CMM8; COMMAD; MI; WS2; WS2A |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_198177 |
ORF Size | 1512 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC211586).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_198177.1 |
RefSeq Size | 4624 bp |
RefSeq ORF | 1515 bp |
Locus ID | 4286 |
UniProt ID | O75030 |
Cytogenetics | 3p13 |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Melanogenesis, Melanoma, Pathways in cancer |
MW | 56.2 kDa |
Gene Summary | The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017] |
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