CTDSP2 (NM_005730) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209026L3V

Lenti ORF particles, CTDSP2 (Myc-DDK tagged) - Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CTDSP2
• Synonyms: OS4; PSR2; SCP2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_005730
• ORF Size: 813 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209026).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005730.3
• RefSeq Size: 5038 bp
• RefSeq ORF: 816 bp
• Locus ID: 10106
• UniProt ID: O14595
• Cytogenetics: 12q14.1
• Domains: CPDc
• Protein Families: Druggable Genome, Phosphatase
• MW: 30.7 kDa
• Gene Summary: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.[UniProtKB/Swiss-Prot Function]