ZMPSTE24 (NM_005857) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206035L1V

Lenti ORF particles, ZMPSTE24 (Myc-DDK tagged) - Human zinc metallopeptidase (STE24 homolog, S. cerevisiae) (ZMPSTE24), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ZMPSTE24
• Synonyms: FACE-1; FACE1; HGPS; PRO1; STE24; Ste24p
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_005857
• ORF Size: 1425 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206035).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005857.3
• RefSeq Size: 3154 bp
• RefSeq ORF: 1428 bp
• Locus ID: 10269
• UniProt ID: O75844
• Cytogenetics: 1p34.2
• Domains: Peptidase_M48
• Protein Families: Druggable Genome, Protease, Transmembrane
• MW: 54.6 kDa
• Gene Summary: This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]