Aph 1b (APH1B) (NM_031301) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205070L3V

Lenti ORF particles, APH1B (Myc-DDK tagged) - Human anterior pharynx defective 1 homolog B (C. elegans) (APH1B), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Aph 1b
• Synonyms: APH-1B; PRO1328; PSFL; TAAV688
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_031301
• ORF Size: 771 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205070).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_031301.2
• RefSeq Size: 4205 bp
• RefSeq ORF: 774 bp
• Locus ID: 83464
• UniProt ID: Q8WW43
• Cytogenetics: 15q22.2
• Protein Families: Transmembrane
• MW: 28.5 kDa
• Gene Summary: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]