FASTK (NM_006712) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC204063L2V
- LentiORF®
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Lenti ORF particles, FASTK (mGFP-tagged) - Human Fas-activated serine/threonine kinase (FASTK), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
AAV Particle: DDK
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | FASTK |
Synonyms | FAST |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_006712 |
ORF Size | 1647 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204063).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006712.3 |
RefSeq Size | 1885 bp |
RefSeq ORF | 1650 bp |
Locus ID | 10922 |
UniProt ID | Q14296 |
Cytogenetics | 7q36.1 |
Protein Families | Druggable Genome, Protein Kinase |
MW | 61.1 kDa |
Gene Summary | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008] |
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