COMMD5 (NM_001081004) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC201051L4V
- LentiORF®
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Lenti ORF particles, COMMD5 (mGFP-tagged) - Human COMM domain containing 5 (COMMD5), transcript variant 3, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
AAV Particle: DDK
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | COMMD5 |
Synonyms | HCARG; HT002 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001081004 |
ORF Size | 672 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201051).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001081004.1 |
RefSeq Size | 1321 bp |
RefSeq ORF | 675 bp |
Locus ID | 28991 |
UniProt ID | Q9GZQ3 |
Cytogenetics | 8q24.3 |
Protein Families | Druggable Genome |
MW | 24.7 kDa |
Gene Summary | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966).[UniProtKB/Swiss-Prot Function] |
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