Zbtb17 (NM_009541) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR224036L4V
- LentiORF®
Lenti ORF particles, Zbtb17 (GFP-tagged) - Mouse zinc finger and BTB domain containing 17 (Zbtb17), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | Zbtb17 |
Synonyms | AA589413; Lp-1; Miz1; mZ13; Zfp100 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_009541 |
ORF Size | 2385 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR224036).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009541.2, NP_033567.2 |
RefSeq Size | 3415 bp |
RefSeq ORF | 2385 bp |
Locus ID | 22642 |
UniProt ID | Q60821 |
Cytogenetics | 4 D3 |
Gene Summary | Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 (By similarity).[UniProtKB/Swiss-Prot Function] |
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