Klb (NM_031180) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR222087L3V
- LentiORF®
Lenti ORF particles, Klb (Myc-DDK-tagged) - Mouse klotho beta (Klb), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK mGFP mGFP w/ Puro
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Klb |
Synonyms | AV071179; betaKlotho |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_031180 |
ORF Size | 3129 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222087).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_031180.2, NP_112457.1 |
RefSeq Size | 3439 bp |
RefSeq ORF | 3132 bp |
Locus ID | 83379 |
UniProt ID | Q99N32 |
Cytogenetics | 5 C3.1 |
Gene Summary | Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.[UniProtKB/Swiss-Prot Function] |
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