Aimp2 (NM_001172146) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR221050L3V

Lenti ORF particles, Aimp2 (Myc-DDK-tagged) - Mouse aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 (Aimp2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Aimp2
• Synonyms: AA407136; AA407225; Aimp2(p38); Jtv1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001172146
• ORF Size: 960 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR221050).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001172146.1, NP_001165617.1
• RefSeq Size: 1210 bp
• RefSeq ORF: 963 bp
• Locus ID: 231872
• UniProt ID: Q8R010
• Cytogenetics: 5 G2
• Gene Summary: Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:12060739). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation (PubMed:12819782). Blocks MDM2-mediated ubiquitination and degradation of p53/TP53 (PubMed:18695251). Functions as a proapoptotic factor (PubMed:16135753).[UniProtKB/Swiss-Prot Function]