Sesn3 (NM_030261) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR220914L4V

Lenti ORF particles, Sesn3 (GFP-tagged) - Mouse sestrin 3 (Sesn3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Sesn3
• Synonyms: 5630400E15Rik; BC003348; SEST3
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_030261
• ORF Size: 1479 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR220914).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_030261.4, NP_084537.2
• RefSeq Size: 2158 bp
• RefSeq ORF: 1479 bp
• Locus ID: 75747
• UniProt ID: Q9CYP7
• Cytogenetics: 9 A1
• Gene Summary: May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25259925). May also regulate the insulin-receptor signaling pathway through activation of TORC2 (PubMed:25377878). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity).[UniProtKB/Swiss-Prot Function]