Daam1 (NM_026102) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR211599L3V

Lenti ORF particles, Daam1 (Myc-DDK-tagged) - Mouse dishevelled associated activator of morphogenesis 1 (Daam1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Daam1
• Synonyms: 1700066F09Rik; 2310028E21Rik; AI503486; E130308H01; mKIAA0666
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_026102
• ORF Size: 3231 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR211599).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_026102.2, NP_080378.2
• RefSeq Size: 6004 bp
• RefSeq ORF: 3234 bp
• Locus ID: 208846
• UniProt ID: Q8BPM0
• Cytogenetics: 12 C3
• Gene Summary: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments (By similarity). Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). Together with DAAM2, required for myocardial maturation and sarcomere assembly (PubMed:26526197).[UniProtKB/Swiss-Prot Function]