Map3k11 (NM_022012) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210947L3V

Lenti ORF particles, Map3k11 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase kinase kinase 11 (Map3k11), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Map3k11
• Synonyms: 2610017K16Rik; Mlk3; PTK1; SPRK
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_022012
• ORF Size: 2550 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR210947).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022012.3, NP_071295.2
• RefSeq Size: 3919 bp
• RefSeq ORF: 2553 bp
• Locus ID: 26403
• UniProt ID: Q80XI6
• Cytogenetics: 19 4.34 cM
• Gene Summary: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle (By similarity).[UniProtKB/Swiss-Prot Function]