Exo1 (NM_012012) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR210902L3V
- LentiORF®
Lenti ORF particles, Exo1 (Myc-DDK-tagged) - Mouse exonuclease 1 (Exo1), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Exo1 |
Synonyms | 5730442G03Rik; Msa |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_012012 |
ORF Size | 2514 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR210902).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_012012.2 |
RefSeq Size | 5506 bp |
RefSeq ORF | 2514 bp |
Locus ID | 26909 |
UniProt ID | Q9QZ11 |
Cytogenetics | 1 81.9 cM |
Gene Summary | 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.[UniProtKB/Swiss-Prot Function] |
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