Gbp5 (NM_153564) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR209198L3V

Lenti ORF particles, Gbp5 (Myc-DDK-tagged) - Mouse guanylate binding protein 5 (Gbp5), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Gbp5
• Synonyms: 5330409J06Rik; Gbp5a
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_153564
• ORF Size: 1773 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR209198).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_153564.2, NP_705792.2
• RefSeq Size: 3021 bp
• RefSeq ORF: 1773 bp
• Locus ID: 229898
• UniProt ID: Q8CFB4
• Cytogenetics: 3 H1
• Gene Summary: As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, inflammasome activating agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, such as GBP1 and GBP2, does not produce GMP (By similarity).[UniProtKB/Swiss-Prot Function]