Dlst (NM_030225) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR207251L3V

Lenti ORF particles, Dlst (Myc-DDK-tagged) - Mouse dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Dlst
• Synonyms: 1600017E01Rik; 4632413C10Rik; 4930529O08Rik; DLTS
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_030225
• ORF Size: 1362 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR207251).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_030225.4, NP_084501.1
• RefSeq Size: 2767 bp
• RefSeq ORF: 1365 bp
• Locus ID: 78920
• UniProt ID: Q9D2G2
• Cytogenetics: 12 D1
• Gene Summary: Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (By similarity). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (By similarity). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity).[UniProtKB/Swiss-Prot Function]