Zbp1 (NM_021394) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR206461L1V
- LentiORF®
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Lenti ORF particles, Zbp1 (Myc-DDK-tagged) - Mouse Z-DNA binding protein 1 (Zbp1), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro mGFP mGFP w/ Puro
AAV Particle: DDK
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Product Images
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Zbp1 |
Synonyms | 2010010H03Rik; Dai; Dlm1; mZaDLM |
Mammalian Cell Selection | None |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_021394 |
ORF Size | 1236 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR206461).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_021394.1, NP_067369.1 |
RefSeq Size | 1988 bp |
RefSeq ORF | 1236 bp |
Locus ID | 58203 |
Cytogenetics | 2 H3 |
Gene Summary | Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3.[UniProtKB/Swiss-Prot Function] |
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