Nr2e1 (NM_152229) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR206005L3V

Lenti ORF particles, Nr2e1 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 2, group E, member 1 (Nr2e1), 200ul, >10^7 TU/mL

Product Images

MR206005L3 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with MR206005L3V particle to overexpress human Nr2e1-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Nr2e1
• Synonyms: fierce; frc; Mtl1; Mtll; tailless; TLL; Tlx; XTLL
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_152229
• ORF Size: 1158 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR206005).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_152229.2
• RefSeq Size: 3233 bp
• RefSeq ORF: 1158 bp
• Locus ID: 21907
• UniProt ID: Q64104
• Cytogenetics: 10 22.89 cM
• Gene Summary: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). Regulates cell cycle progression in neural stem cells of rhe developing brain. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells.[UniProtKB/Swiss-Prot Function]