Jazf1 (NM_001168277) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR201591L3V
- LentiORF®
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Lenti ORF particles, Jazf1 (Myc-DDK-tagged) - Mouse JAZF zinc finger 1 (Jazf1), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Jazf1 |
Synonyms | AI591476; C820002C15; Jaz1; Tip27 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001168277 |
ORF Size | 540 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR201591).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001168277.1, NP_001161749.1 |
RefSeq Size | 2926 bp |
RefSeq ORF | 540 bp |
Locus ID | 231986 |
UniProt ID | Q80ZQ5 |
Cytogenetics | 6 25.74 cM |
Gene Summary | Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2 (By similarity). Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (PubMed:24380856). Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (PubMed:24930994). Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (PubMed:24380856, PubMed:25614086). Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (PubMed:25614086, PubMed:24380856).[UniProtKB/Swiss-Prot Function] |
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