AMOTL2 (NM_001278685) Human Untagged Clone

CAT#: SC337436

AMOTL2 (untagged) - Human angiomotin like 2 (AMOTL2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AMOTL2
• Synonyms: LCCP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001278685, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGACACTGGAAGACTCCTCGGGGACAGTCCTGCACCGCCTCATCCAGGAGCAGCTGCGCTACGGCA
  ACCTGACTGAGACGCGCACGCTGCTAGCCATCCAGCAGCAGGCCCTGAGGGGTGGGGCTGGAACTGGGGG
  TACAGGGAGCCCCCAGGCCTCCCTGGAGATCCTGGCCCCAGAGGACAGTCAGGTGCTGCAGCAGGCCACC
  AGGCAGGAGCCCCAGGGCCAGGAGCACCAGGGCGGTGAGAACCACCTGGCAGAGAACACCCTCTACCGGC
  TATGCCCACAGCCCAGCAAGGGAGAGGAGCTGCCCACCTATGAGGAGGCCAAAGCCCACTCGCAGTACTA
  TGCGGCCCAGCAGGCAGGGACCCGGCCACATGCGGGGGACCGAGATCCCCGTGGGGCCCCGGGAGGCAGT
  CGGAGGCAGGACGAGGCCCTGCGGGAGCTGAGGCATGGGCACGTGCGCTCGTTGAGTGAACGGCTCCTTC
  AGTTGTCCCTGGAGAGGAACGGCGCCCGGGCCCCCAGCCACATGAGCTCCTCCCACAGCTTCCCACAGCT
  GGCCCGCAACCAGCAGGGCCCCCCACTGAGGGGCCCCCCTGCTGAGGGCCCAGAGTCCCGAGGACCCCCA
  CCTCAGTACCCTCATGTTGTACTAGCTCATGAGACCACCACTGCTGTCACTGACCCACGGTACCGTGCCC
  GCGGCAGCCCGCACTTCCAGCATGCTGAAGTCAGGATCCTGCAGGCCCAGGTGCCTCCTGTGTTCCTCCA
  ACAGCAGCAGCAGTACCAGTACCTGCAGCAATCTCAGGAGCACCCCCCTCCCCCACATCCAGCTGCTCTC
  GGCCATGGCCCCCTGAGCTCCCTCAGTCCACCTGCTGTGGAGGGGCCAGTGAGTGCCCAGGCCTCCTCAG
  CCACCTCGGGCAGTGCCCACCTGGCCCAGATGGAGGCCGTGCTGAGGGAGAATGCCAGGCTGCAGAGAGA
  CAATGAGCGGCTGCAGAGGGAGCTGGAGAGCTCTGCGGAGAAGGCTGGCCGCATTGAGAAGCTGGAAAGC
  GAAATCCAGCGGCTCTCTGAGGCCCATGAGAGCCTGACCAGAGCCTCCTCCAAGCGTGAGGCCCTGGAGA
  AGACCATGCGGAACAAGATGGACAGTGAAATGAGGAGGCTGCAAGACTTCAACCGGGATCTTAGAGAGAG
  ATTGGAATCTGCAAATCGCCGCCTGGCAAGCAAGACACAGGAGGCCCAGGCCGGCAGTCAGGACATGGTG
  GCCAAGCTGCTTGCTCAGAGCTACGAACAGCAGCAGGAGCAAGAGAAGCTGGAGCGAGAGATGGCACTGC
  TGCGCGGCGCCATCGAGGACCAGCGGCGGCGTGCCGAGCTGCTGGAGCAGGCTCTGGGCAATGCGCAGGG
  CCGGGCAGCTCGAGCCGAAGAGGAGCTGCGCAAGAAGCAGGCCTATGTGGAGAAAGTGGAGCGGCTGCAG
  CAGGCGCTCGGGCAGCTGCAGGCAGCCTGTGAGAAGCGGGAGCAGCTGGAGCTGCGTCTGCGGACTCGCC
  TGGAGCAGGAACTCAAGGCCCTGCGTGCACAGCAGGCAGGTGCCCCAGGTGGTAGCAGTGGCAGTGGTGG
  GTCTCCAGAGCTCAGCGCCCTGCGACTGTCAGAACAACTGCGAGAGAAGGAGGAGCAGATCCTGGCGCTG
  GAGGCCGACATGACCAAGTGGGAGCAGAAGTATTTGGAGGAACGTGCCATGAGGCAGTTTGCCATGGATG
  CGGCTGCCACGGCTGCTGCTCAGCGTGACACCACTCTCATCCGACATTCCCCCCAGCCCTCACCCAGCAG
  CAGCTTCAATGAGGGTCTGCTCACTGGTGGCCACAGGCATCAGGAGATGGAAAGCAGGTTAAAGGTGCTC
  CATGCCCAGATCCTGGAGAAGGATGCAGTGATCAAGGTCCTTCAGCAGCGCTCCAGGAGAGACCCTGGCA
  AGGCCATCCAGGGCTCCCTGCGGCCTGCCAAGTCGGTGCCATCTGTTTTCGCGGCTGCGGCAGCAGGAAC
  CCAGGGCTGGCAAGGGCTCTCTTCTAGTGAGCGACAAACAGCAGACGCCCCTGCTCGGCTGACTACAGAC
  AGAGCACCCACAGAGGAGCCAGTGGTCACAGCTCCCCCTGCTGCCCATGCCAAACACGGGAGCAGAGATG
  GGAGCACCCAGACTGAGGGCCCCCCAGACAGCACCTCCACCTGCCTGCCACCGGAGCCTGACAGCCTTCT
  GGGGTGCAGCAGTAGCCAGAGAGCAGCCTCTCTGGACTCTGTAGCTACATCCAGAGTCCAGGACTTGTCA
  GACATGGTGGAGATACTGATCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001278685
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001278685.1, NP_001265614.1
• RefSeq Size: 4999 bp
• RefSeq ORF: 2334 bp
• Locus ID: 51421
• UniProt ID: Q9Y2J4
• Cytogenetics: 3q22.2
• Gene Summary: Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (3) differs in the 5' UTR, uses an alternate in-frame splice site in the 3' coding region and initiates translation at a downstream start site, compared to variant 1. It encodes isoform 3, which is shorter at the N-terminus and lacks two internal amino acids compared to isoform 1.