GMPR2 (NM_001283021) Human Untagged Clone

CAT#: SC335708

GMPR2 (untagged) - Human guanosine monophosphate reductase 2 (GMPR2), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GMPR2
• Synonyms: GMPR 2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC335708 representing NM_001283021.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGGATGTGTTTTTCTTATATACAAGTTGTTCACTTTGAAATGGAAGATGCTGCTCCTGTCAGTACTA
  TTACCTGCCTCTATACTTGTTGCTGAGAAGTTCTCTCTCTTCACTGCTGTCCATAAGCACTATAGCCTC
  GTTCAGTGGCAAGAGTTTGCTGGCCAGAATCCTGACTGTCTTGAGCATCTGGCTGCCAGCTCAGGCACA
  GGCTCTTCTGACTTTGAGCAGCTGGAACAGATCCTGGAAGCTATTCCCCAGGTGAAGTATATATGCCTG
  GATGTGGCAAATGGCTACTCTGAACACTTTGTTGAATTTGTAAAAGATGTACGGAAGCGCTTCCCCCAG
  CACACCATCATGGCAGGGAATGTGGTAACAGGAGAGATGGTAGAAGAGCTCATCCTTTCTGGGGCTGAC
  ATCATCAAAGTGGGAATTGGGCCAGGCTCTGTGTGTACTACTCGGAAGAAAACTGGAGTGGGGTATCCA
  CAGCTCAGCGCAGTGATGGAGTGTGCAGATGCTGCTCATGGCCTCAAAGGCCACATCATTTCAGATGGA
  GGTTGCAGCTGTCCTGGGGATGTGGCCAAGGCTTTTGGGGCAGGAGCTGACTTCGTGATGCTGGGTGGC
  ATGCTGGCTGGGCACAGTGAGTCAGGTGGTGAGCTCATCGAGAGGGATGGCAAGAAGTACAAGCTCTTC
  TATGGAATGAGTTCTGAAATGGCCATGAAGAAGTATGCTGGGGGCGTGGCTGAGTACAGGTATGTGTGG
  AGGCCCAGGAGCTTAGTAATAGTATGGAGGCAGAACTCATGGCTGCTGAGAGGGGGATGGTACAGTTCT
  CAGAGAAGCATGGTGAACCGGGGCTCAATGCTAGGGTCTGTGGAAAAGTCCCTGGGCTTAAGGAATCCA
  GAAGGAGAAGATAATAAAGTTTTTCCTACTTTAAGAGCCTCAGAGGGAAAGACAGTGGAAGTTCCTTTT
  AAAGGAGATGTGGAACATACCATCCGAGACATCCTAGGAGGGATCCGCTCTACGTGTACCTATGTGGGA
  GCAGCTAAGCTCAAAGAGTTGAGCAGGAGAACTACCTTCATCCGAGTCACCCAGCAGGTGAATCCAATC
  TTCAGTGAGGCGTGCTAG
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001283021
• Insert Size: 1122 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001283021.1
• RefSeq Size: 2248 bp
• RefSeq ORF: 1122 bp
• Locus ID: 51292
• UniProt ID: Q9P2T1
• Cytogenetics: 14q12
• Protein Families: Druggable Genome
• Protein Pathways: Purine metabolism
• MW: 40.9 kDa
• Gene Summary: This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of guanosine monophosphate (GMP) to inosine monophosphate (IMP). The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
  Transcript Variant: This variant (5) differs in the 5' UTR and contains multiple differences in the coding region, compared to variant 1, including initiation of translation at an alternate start codon. The encoded isoform (3) is longer and has a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.