CFHR4 (NM_001201550) Human Untagged Clone
CAT#: SC331439
CFHR4 (untagged) - Homo sapiens complement factor H-related 4 (CFHR4), transcript variant 1
"NM_001201550" in other vectors (2)
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | CFHR4 |
Synonyms | CFHL4; FHR-4; FHR4 |
Vector | pCMV6-Entry |
Restriction Sites | SgfI-RsrII |
ACCN | NM_001201550 |
Insert Size | 1737 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001201550.2 |
RefSeq Size | 2181 bp |
RefSeq ORF | 1737 bp |
Locus ID | 10877 |
UniProt ID | Q92496 |
Cytogenetics | 1q31.3 |
Protein Families | Secreted Protein |
MW | 65.4 kDa |
Gene Summary | This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011] Transcript Variant: This variant (1) encodes the longest isoform (1, also known as FHR-4A). |
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