USP19 (NM_001199162) Human Untagged Clone

CAT#: SC331255

USP19 (untagged) - Homo sapiens ubiquitin specific peptidase 19 (USP19), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USP19
• Synonyms: ZMYND9
• Vector: pCMV6-Entry
• Sequence Data:
  Fully Sequenced ORF

  >SC331255 representing NM_001199162.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  ATGTCTGGCGGGGCCAGTGCCACAGGCCCAAGGAGAGGGCCCCCAGGACTGGAGGACACCACTAGTAAG
  AAGAAGCAGAAGGATCGAGCAAACCAGGAGAGCAAGGATGGAGATCCTAGGAAAGAGACAGGGTCTCGA
  TATGTTGCCCAGGCTGGTCTTGAACCTCTGGCCTCAGGTGATCCTTCTGCCTCAGCCTCCCATGCAGCT
  GGGATCACAGGCTCACGCCACCGTACCCGGCTGTTCTTTCCTTCATCGTCAGGGTCAGCATCCACTCCT
  CAAGAGGAGCAGACCAAAGAGGGAGCTTGTGAAGACCCTCATGATCTCTTGGCTACTCCCACTCCAGAG
  TTGTTGCTCGATTGGAGGCAGAGTGCAGAAGAGGTGATTGTCAAGCTTCGTGTGGGAGTAGGTCCCCTG
  CAGCTGGAGGATGTAGATGCTGCTTTCACAGATACAGACTGTGTGGTGCGGTTTGCAGGTGGTCAGCAG
  TGGGGTGGTGTCTTCTATGCTGAGATAAAAAGCTCTTGTGCTAAAGTGCAAACCCGCAAGGGCAGTCTC
  CTGCACCTGACACTGCCCAAAAAGAAGAAACCTCTAGGGACCCAGGAGCTGGTGCCGGGGCTGCGGTGC
  CAGGAGAATGGGCAGGAACTGTCTCCCATTGCCCTGGAGCCAGGCCCTGAGCCCCACCGGGCTAAGCAG
  GAGGCCCGGAACCAGAAGCGGGCCCAGGGCCGTGGTGAGGTAGGCGCAGGGGCTGGCCCCGGGGCCCAG
  GCAGGGCCCAGCGCCAAGAGGGCTGTGCATCTCTGCAGAGGGCCAGAGGGGGACGGGTCCAGGGATGAC
  CCTGGACCCCGGGGTGATGCCCCACCCTTCGTGGCTGACCCAGCCACCCAGGTTGAGGCTGATGAACAG
  CTTTGCATACCACCGCTGAACTCCCAAACCTGCCTCCTGGGCTCAGAGGAGAATTTAGCCCCTTTGGCA
  GGAGAGAAAGCAGTGCCTCCCGGGAATGACCCAGTCTCTCCAGCCATGGTCCGGAGCAGAAACCCTGGG
  AAAGATGACTGTGCCAAGGAGGAGATGGCAGTGGCAGCAGATGCTGCAACCTTGGTGGATGAGCCCGAG
  TCGATGGTGAACCTGGCGTTTGTCAAGAATGACTCGTATGAGAAGGGCCCGGATTCAGTGGTGGTGCAC
  GTGTACGTGAAGGAGATCTGCAGGGACACCTCAAGAGTACTTTTCCGTGAGCAGGACTTCACGCTCATC
  TTCCAGACCAGGGATGGAAACTTCCTGAGGCTGCACCCGGGCTGTGGGCCCCACACCACCTTCCGTTGG
  CAGGTGAAGCTCAGGAATCTGATTGAGCCAGAGCAGTGCACCTTCTGTTTCACGGCTTCTCGCATCGAC
  ATCTGCCTTCGTAAGAGGCAGAGTCAGCGCTGGGGGGGCCTGGAGGCCCCGGCTGCACGAGTGGGTGGT
  GCAAAGGTTGCCGTGCCGACAGGTCCAACCCCTCTGGATTCAACCCCACCAGGAGGTGCTCCCCACCCC
  CTGACAGGCCAGGAGGAGGCCCGGGCTGTGGAGAAGGATAAATCCAAGGCACGATCTGAGGACACAGGG
  CTAGACAGTGTGGCAACCCGCACACCCATGGAGCATGTAACCCCAAAGCCAGAGACACACCTGGCCTCG
  CCCAAGCCTACATGCATGGTGCCTCCCATGCCCCACAGCCCAGTTAGTGGAGACAGCGTGGAGGAGGAG
  GAAGAGGAAGAGAAGAAGGTGTGTCTGCCAGGCTTCACTGGCCTTGTCAATTTAGGCAACACCTGCTTC
  ATGAACAGCGTCATTCAGTCTCTGTCCAACACTCGGGAACTCCGGGACTTCTTCCATGACCGCTCCTTT
  GAGGCTGAGATCAACTACAACAACCCACTAGGGACTGGTGGGCGTCTGGCCATTGGCTTTGCCGTGCTG
  CTTCGGGCGCTGTGGAAGGGCACCCACCATGCCTTCCAGCCTTCCAAGTTGAAGGCCATTGTGGCGAGT
  AAGGCCAGCCAGTTCACAGGCTATGCACAGCATGATGCCCAGGAGTTCATGGCTTTCCTGCTGGATGGG
  CTGCACGAGGACCTGAATCGCATTCAGAACAAGCCCTACACAGAGACCGTGGATTCAGATGGGCGGCCC
  GATGAGGTGGTAGCTGAGGAAGCATGGCAGCGGCACAAGATGAGGAATGACTCTTTCATCGTGGACCTA
  TTTCAGGGGCAGTACAAGTCGAAGCTGGTGTGCCCTGTGTGTGCCAAGGTCTCCATCACTTTTGACCCG
  TTTCTTTATCTGCCGGTGCCCTTGCCACAAAAGCAAAAGGTTCTCCCTGTCTTTTATTTTGCCCGAGAG
  CCCCACAGCAAGCCCATCAAGTTCCTGGTGAGCGTCAGCAAGGAGAACTCCACTGCGAGCGAAGTATTG
  GACTCCCTCTCTCAGAGTGTTCATGTGAAGCCTGAGAACCTGCGTTTGGCGGAGGTAATTAAGAATCGT
  TTTCATCGTGTGTTCCTACCCTCCCACTCACTGGACACTGTGTCCCCATCTGATACGCTCCTCTGCTTT
  GAGCTGCTATCCTCAGAGTTGGCTAAGGAGCGGGTAGTGGTGCTAGAGGTGCAACAGCGCCCCCAGGTG
  CCCAGCGTCCCCATCTCCAAGTGTGCAGCCTGCCAGCGGAAGCAACAGTCGGAGGATGAAAAGCTGAAG
  CGCTGTACCCGGTGCTACCGTGTGGGCTACTGCAACCAGCTCTGCCAGAAAACCCACTGGCCTGACCAC
  AAGGGCCTCTGCCGACCTGAGAACATTGGCTACCCCTTCCTGGTCAGTGTACCTGCCTCACGCCTCACT
  TATGCCCGCCTCGCTCAGTTGCTAGAGGGCTATGCCCGGTACTCTGTGAGTGTATTCCAGCCACCCTTT
  CAGCCAGGCCGCATGGCCTTGGAGTCTCAGAGCCCTGGCTGCACCACACTGCTCTCCACAGGTTCCCTG
  GAGGCTGGGGACAGCGAGAGAGACCCCATTCAGCCACCTGAGCTCCAGCTGGTGACCCCTATGGCTGAG
  GGGGACACAGGGCTTCCCCGGGTGTGGGCAGCCCCTGACCGGGGTCCTGTGCCCAGCACCAGTGGAATT
  TCTTCTGAGATGCTGGCCAGTGGGCCCATTGAGGTTGGCTCCTTGCCAGCTGGCGAGAGGGTGTCCCGA
  CCCGAAGCTGCTGTGCCTGGGTACCAGCATCCAAGTGAAGCTATGAATGCCCACACACCCCAGTTCTTC
  ATCTATAAAATTGATTCATCCAACCGAGAGCAGCGGCTAGAGGACAAAGGAGACACCCCACTGGAGCTG
  GGTGACGACTGTAGCCTGGCTCTCGTCTGGCGGAACAATGAGCGCTTGCAGGAGTTTGTGTTGGTAGCC
  TCCAAGGAGCTGGAATGTGCTGAGGATCCAGGCTCTGCCGGTGAGGCTGCCCGGGCCGGCCACTTCACC
  CTGGACCAGTGCCTCAACCTCTTCACACGGCCTGAGGTGCTGGCACCCGAGGAGGCCTGGTACTGCCCA
  CAGTGCAAACAGCACCGTGAGGCCTCCAAGCAGCTGTTGCTATGGCGCCTGCCAAATGTTCTCATCGTG
  CAGCTCAAGCGCTTCTCCTTTCGTAGTTTTATCTGGCGTGACAAGATCAATGACTTGGTGGAGTTCCCT
  GTTAGGAACCTGGACCTGAGCAAGTTCTGCATTGGTCAGAAAGAGGAGCAGCTGCCCAGCTACGATCTA
  TATGCTGTCATCAACCACTATGGAGGCATGATTGGTGGCCACTACACTGCCTGTGCACGCCTGCCCAAT
  GATCGTAGCAGTCAGCGCAGTGACGTGGGCTGGCGCTTGTTTGATGACAGCACAGTGACAACGGTAGAC
  GAGAGCCAGGTTGTGACGCGTTATGCCTATGTACTCTTCTACCGCCGGCGGAACTCTCCTGTGGAGAGG
  CCCCCCAGGGCAGGTCACTCTGAGCACCACCCAGACCTAGGCCCTGCAGCTGAGGCTGCTGCCAGCCAG
  GGACTAGGCCCTGGCCAGGCCCCCGAGGTGGCCCCCACGCGGACAGCCCCTGAACGCTTCGCCCCCCCT
  GTGGATCGGCCAGCCCCCACCTACAGCAACATGGAGGAGGTGGATTAG
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001199162
• Insert Size: 4119 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001199162.1
• RefSeq Size: 4847 bp
• RefSeq ORF: 4119 bp
• Locus ID: 10869
• UniProt ID: O94966
• Cytogenetics: 3p21.31
• Protein Families: Druggable Genome, Protease, Transmembrane
• MW: 150.7 kDa
• Gene Summary: Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (3) has an alternate splice site in the CDS and an alternate 3' exon, as compared to variant 1. The resulting isoform (2) lacks an internal segment and has a shorter and distinct C-terminus, as compared to isoform 1.