NPAS3 (NM_001165893) Human Untagged Clone

CAT#: SC327248

NPAS3 (untagged)-Human neuronal PAS domain protein 3 (NPAS3) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NPAS3
• Synonyms: bHLHe12; MOP6; PASD6
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001165893 edited
  GAATTCATGGCGCCCACCAAGCCCAGCTTTCAGCAGGATCCTTCCAGGCGAGAACGTTTA
  CAAGCATTGAGAAAGGAGAAATCCCGAGATGCTGCTCGCTCCCGCCGGGGAAAAGAAAAC
  TTTGAGTTCTATGAATTGGCCAAGTTGTTGCCTCTTCCTGCAGCCATTACCAGCCAGCTC
  GACAAGGCATCCATCATTCGACTTACAATTAGCTATCTGAAAATGAGGGACTTTGCTAAC
  CAGGGGGACCCTCCGTGGAACTTGCGAATGGAAGGCCCTCCACCTAACACATCAGTAAAA
  GTTATAGGTGCACAGCGAAGGAGAAGCCCCAGTGCACTAGCCATTGAAGTATTTGAAGCA
  CATTTGGGAAGCCACATTTTGCAGTCCCTGGATGGCTTTGTATTTGCACTAAATCAGGAA
  GGAAAATTTTTGTACATTTCCGAAACAGTCTCCATCTACCTAGGCCTCTCACAAGTGGAG
  CTGACAGGCAGCAGTGTCTTTGACTATGTCCACCCCGGAGATCACGTGGAGATGGCTGAG
  CAGCTGGGCATGAAGCTCCCCCCTGGGCGGGGTCTCCTGTCACAGGGCACTGCTGAGGAC
  GGAGCCAGCTCAGCATCTTCCTCCTCTCAGTCGGAGACCCCCGAGCCAGTGGAGTCAACC
  AGCCCCAGTCTGCTAACCACTGACAACACTCTTGAGCGTTCCTTTTTCATCCGAATGAAA
  TCTACTCTGACCAAACGCGGTGTGCACATCAAATCATCAGGATATAAGGTGATTCACATA
  ACAGGCCGGCTACGCCTGAGAGTGTCGCTGTCCCACGGGAGGACCGTCCCCAGCCAAATC
  ATGGGTCTCGTGGTTGTTGCGCATGCCTTGCCTCCCCCTACGATCAATGAAGTCAGAATT
  GACTGCCATATGTTCGTCACTCGAGTAAATATGGACCTCAATATCATTTACTGTGAAAAT
  AGGATTAGTGATTATATGGATCTGACCCCTGTAGATATCGTAGGGAAGAGATGCTACCAC
  TTCATCCATGCTGAAGACGTGGAGGGCATCAGGCACAGTCACTTGGACTTGCTGAATAAG
  GGTCAGTGTGTGACAAAGTACTATCGCTGGATGCAGAAGAACGGAGGATATATTTGGATA
  CAGTCCAGTGCCACCATAGCTATTAATGCCAAGAATGCAAATGAAAAGAATATCATCTGG
  GTGAATTACCTTCTTAGCAATCCTGAGTACAAGGACACACCCATGGACATCGCACAGCTC
  CCCCATCTGCCGGAGAAAACTTCCGAATCCTCGGAGACATCCGACTCTGAGTCAGACTCT
  AAAGACACCTCAGGTATTACAGAGGACAACGAGAACTCCAAGTCCGACGAGAAGGGGAAC
  CAGTCCGAGAACAGCGAAGACCCGGAGCCCGACCGGAAGAAGTCGGGCAACGCGTGTGAC
  AACGACATGAACTGCAACGACGACGGCCACAGCTCCAGTAACCCGGACAGCCGCGACAGC
  GACGACAGCTTCGAGCACTCGGACTTTGAGAACCCCAAGGCGGGCGAGGACGGCTTCGGT
  GCTCTGGGCGCGATGCAGATCAAGGTGGAGCGCTACGTGGAGAGCGAGTCGGACCTGCGG
  CTGCAGAACTGCGAGTCACTCACGTCCGACAGCGCCAAGGACTCGGACAGCGCAGGCGAG
  GCGGGCGCGCAGGCCTCCAGCAAGCACCAGAAGCGCAAGAAAAGGCGGAAACGGCAAAAG
  GGCGGCAGCGCCAGCCGCCGGCGCCTGTCCAGCGCGTCGAGCCCAGGCGGCCTGGACGCG
  GGCCTGGTGGAGCCCCCGCGGCTGCTGTCCTCCCCCAACAGTGCCTCGGTGCTCAAGATC
  AAGACGGAGATCTCAGAACCCATCAATTTCGACAATGACAGCAGCATCTGGAACTACCCG
  CCCAACCGGGAGATCTCCAGGAACGAGTCCCCCTACAGCATGACCAAGCCCCCCAGCTCT
  GAGCACTTCCCGTCCCCGCAGGGCGGCGGCGGTGGGGGTGGCGGTGGCGGGGGGCTGCAC
  GTGGCCATTCCCGACTCGGTCCTCACCCCGCCCGGCGCCGACGGCGCGGCCGCCCGCAAG
  ACTCAGTTCGGCGCCTCGGCCACCGCGGCCCTGGCCCCCGTCGCCTCCGACCCGCTGTCA
  CCCCCGCTCTCGGCGTCCCCGCGGGACAAGCACCCCGGGAACGGCGGCGGGGGCGGGGGC
  GGGGGCGGCGGCGCGGGGGGCGGCGGCCCCAGCGCGTCCAACTCCTTGCTGTACACTGGG
  GACCTGGAGGCGCTGCAGAGGTTGCAGGCGGGCAACGTCGTGCTCCCGCTGGTGCACAGG
  GTGACCGGGACCCTGGCCGCCACCAGCACGGCCGCGCAGAGGGTCTACACCACGGGCACC
  ATCCGCTACGCGCCCGCCGAGGTGACCCTGGCCATGCAGAGCAACCTGCTGCCCAACGCG
  CACGCTGTTAACTTCGTGGACGTTAACAGCCCCGGCTTTGGCCTCGACCCCAAGACGCCC
  ATGGAGATGCTCTACCACCACGTGCACCGGCTCAACATGTCAGGACCGTTCGGCGGCGCA
  GTGAGCGCAGCTAGCCTGACGCAGATGCCCGCCGGCAACGTGTTCACCACGGCCGAGGGA
  CTCTTCTCCACGCTGCCCTTCCCCGTCTACAGCAACGGCATCCACGCGGCACAGACTCTG
  GAGCGCAAGGAGGACTGATCTAGATCTC
  
• Restriction Sites: Please inquire
• ACCN: NM_001165893
• Insert Size: 2700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001165893.1.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001165893.1, NP_001159365.1
• RefSeq Size: 5849 bp
• RefSeq ORF: 2712 bp
• Locus ID: 64067
• UniProt ID: Q8IXF0
• Cytogenetics: 14q13.1
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
  Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (4) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.