EXPH5 (NM_001144765) Human Untagged Clone

CAT#: SC325421

EXPH5 (untagged)-Human exophilin 5 (EXPH5), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXPH5
• Synonyms: SLAC2-B; SLAC2B
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001144765, the custom clone sequence may differ by one or more nucleotides
  ATGAGGGAGGAGAGTGGCATGCCTCCACCGTGGGATGCTTCACTGCTGGAGAATGAGTTT
  TTCCAAGTTTTAGATGACTTGGATAGCAAATTGGCTCAGGAACAGTCTGCAAGCTCAGTG
  AATACCAGAACACCCCTCAACTATGGATCAAGAACACAGTTCGGTCACTTTTATTCCAGT
  GGTAACAGACATGGTAATATCACAGAAAGGCACAAAAAACACTATAATGAAACTTCCAAT
  ATGTCTATCTATGACATCCTAAGACCAGGAACTCCTAGGGAAGGTTTTAAAACCTTTTCT
  CCTAGGACAAGCACAATTTATGATATGTATAGGACAAGGGAGCCCAGAGTCTTTAAAGAA
  GATTATGTGCAAAAGAATACTTTTGGCAGTACTTCGCTGTGTTTTGACAGCAGGCAACGG
  TCGGCCTTACCAGCCACAGGGCATTTCACAGCAAGAAGCTTACATTTTCCAGCCACAACT
  CAGAGCAAGAGTGGGTTTATACCACCAAGGCACCAGCAGAGTCCAAAGAGAACTCCTTTA
  TCATCCATCATATGGAACAGATCAGATTCCTCTAGAGACAGGGAGAACCAGGAAGAGTTC
  CTGAGGGCACCATCACCAATGGAAATTGATCCCGCTGACAAGTATGTGTATCCCAGGGGT
  TTTCAGGAGAATAAGAGATATGAATCGTACCATTCACAGAATGTTTACCAACGTGTTAGT
  TTAAATGCTCCCATGGAGAATGCAATGAGTCCCGACACTTTTGAGAACTCAGAGAACATG
  CCATTCTACCATCAAAGCAACACATTTACCAGATCTTTCTTCAGCAATACCTTTGGACGA
  AGCGGAGAACAGAGGAGATTTGGACAAGGTCCTTTTTGGGGCCAAGAGAAAGGACATTCT
  TTCTGGTCTGACTTTCATCGAAGCAGGAAATCATTCAGTTCTTCTGACAGAGACTTTGAA
  ATGATTTCCATGGAAGCAAATAGTGTATCAGCCATTCATGGCCATAATGTTTCTTCTGAA
  CACTGGGAATCATTTTCTTCTGGTTATGGAACAGATGTTTCCAGAGGCCAAGAAGAGCCA
  CATCCTTGGCAGTTTGATTTTCAGAGATCCACACTGGATAGCATGGTGGTATCACATGGT
  AATGAGACCCAGTTGACTCCTCATTTTGGCACACCAAATGTTTGCTCCATGACTGGTTCA
  AGCTATCACGTCAAATCTAGTGAGTTGGTAAGTCAACAGGACAGTTCTCCTGTAGAAGTA
  CATATAAACAAAGAAGCTTCCTCATTTGGAATTGCTCAGACTCTAGCATCCTCATTCAAA
  ACTTCCTTTTCCCAGATTTCTGATGACAGAAGGAATCCTCAGAGTCCCAACTTGCAGAAT
  CCCACAGTCACTTTGCAGAAAATTTTTCCAAATAAGCCTGCCTCTCATCCAATGAGAAGC
  CATACAGAAGTCACTGTGACCAGCAGCAATTCAGTTGACTCTCTGCCTCTTGCCAAAAGC
  CAGCCCAATATCTTGGTCACAGAAGTAAATAATGAGAAAGACTTAAATGAATCTATTTCA
  GAAGAAGACAAACAGCTAAGCAAGATGGACCAGACAAACAAGGCAGGTGAAATACCCCAA
  CCTGTTTCACAGACAGGGATCTCAAACTCTTTACCTGATTTTCAAAATCCCTTATCCCAG
  GACTCAGCCAAGAGCAACGGGTTTGGTTTTAATGCATCTACCATAATAAGTTCAAAAAAG
  TCACCCAGAGTCTTTTCCAGGAAAGATACCTCCAAAATGTATATACCGCACACAGATAAA
  TCCAATGACATTAAACAAGATAAGAGGTTTACTGAAAACAGAAAACTTGGCTCAACAGCT
  TCCCTTCCTTTCATTCAGGAACACAGAACACCACCATCTTTCCCCAGGACAGACCAAGGT
  TGTCACCAGGAATTAACTGTAAATAATGAAGATATTTCAAGAATTATTACAAATAACCAC
  TGGAGCTCTGCACTGACTGATACTCAAAATGCACAATACTCAAAATGCAAGTTAACTCCT
  GGCCACAAGACCTCGTGTGATTCTTTAGATCTGTCATCAGCTGCACTACCAGATTCCTCA
  CCATCAAAGAATTCTTCCCTTGATGCTCCTGTGGTTCCATCTACTACAGTGTTCTCCAGG
  AGAAGTCCTTCAGACAAAGATCCATCGCTAGGAGAAAGAGAAGAAAAAGACAATGCTGGG
  AAGAACCAAAAGAATCAGTTTATTGTAAGCCACTCAGAAAACCAAGAGAGAAATGATAGT
  CCTGTGCCTACACATGATGAAGTGGTTGATGTCAAATGCCATTCACACTCTCCTTTTAGG
  AATGAAAGAGGAAAAGGAAAAATAAGGCATCATATATCCTGTATTGAAAAGTTAAGCAAA
  ACAGAAAGTATATCAGTACCCACCAGTGATCACAGGAGCCTCATTGAAGCAAATCAAAGC
  AATTCCAAAGTTTCTGAACTTGACACAATTTATTGTACCTTGCCAAGAAAATCAAGCAGT
  TTTCTCATACATGGCAGGCAGTCAGGAAGTAAAATAATGGCTGCTTCATTGAGGAATGGG
  CCACCTCCCTTCCAAATCAAAAATAATGTGGAAGATGCAATGGGGAACTATATGTTAAAC
  AAATTTAGTCCCAGTTCTCCTGAGTCAGCGAATGAATGTTCCAAAGTCCTTTCAGACTCA
  GCCCTGGAAGCACCTGAAGCCACAGAGAGAATGACAAATGTAAAAAGCAGTGGATCTACT
  TCCGTTAGAAAAGGACCACTTCCATTCCTCATCAACAGGGCTATGTCATGTCCCTCAGGG
  GAGCCACATGCCTCAACTGGAAGAGAAGGAAGAAAAAAGCCATTGACCTCAGGCATGGAT
  GCTTCTGAGCTAACACCAAGGGCTTGGGAGAGAATCATTAGCCCTGTGGAAAGTGACTCA
  TCTGTTAGAGATTGTTCTTTAACCAAAAGACAACACCAAAAGGAAAACTTCCAAGAATAC
  ACTGAGAAAGAGGGTAAAATGGCTGCCTCCAGGAGAAGTGTATTTGCTCTTTCAAATGAA
  GACCCTTTACCTTTTTGCTCAGACTTGTCAGGAAAAGAACGTGGGAAAACATTACATAAA
  GTTAAGACGACTAGTACGTTTTCTGTTTCTGGTGATGAAGATAATGTAAAATGTCTGGAG
  GTGGTCTCAATATATTACACTCTACCGAGGAAACCCAGCAAAAAATTCTGTAACCTCCTT
  CAACAGTATACACAAAATACTAATTTACTTATAGAATCACCTCAAGTGGAGACTGAAACA
  TTTCCTAACGCTTTAGAAAAAGACAAACAGAATTATTCTACACGAGAGCAGTCAGGAACA
  CCTTCATGTGAAAATCTAAAGATGTCCGTCAACTCTGATCAGACGCTCACCACTGAAAAT
  ATGACTGCCTTCCGATTATCAAATAGGGGGCCCCTAGCTCCTACATTACAGGAAATGGCT
  TCTGTTGAGGCAGCTGTTTCTCTTCCTGAAGAGGAATCTAAAGCTAGAGAGATTTTTTCA
  GATAATTTAGCTAAAACACCTCTAGGTGATTCAGAAAACAAGAAGGAAAGAGGCAAAAAG
  TTGCAAAGTGAAACCCTGCATACTTCATTGATGCTTCAGAGAAAAAATGTATCCGAAGAA
  AAATCTGAAAATTGTCAACAATCCATTAATTCAAGTAACAGTGGTCCCTCTAGTCTTCCA
  GCTCTTTCAGAAGTTAATATTGGAAATTCCCAAACTAGAAGAAGTTCTTGGGAGTGTACA
  GGGAGTGGTAGAGCCATTCCATTTACTGGAAGTGGCAAGTGTCCCCAGAAAGATCACACA
  TCCACAGCTGTAGGTGATGGCTCCAGTGGATCACAGCCTAGGGAAGGCAGAGGGGACATT
  GGAACCAACTGCCAAAAAATGACTAATAAAACACTTTCTCACTCAGAGAGTCAAGTCTTT
  GCCCTTACTCCAGCATTGCATAAACTACAGCTTGGTGAGGAGACTCAGTCAGATGAACCA
  AACTTAGAGAGTCTGCAGTCTGAACCAAGAGAATTACCTCAAAGAAGTCAGGAGGCAAAT
  ATGACAGAGAGCAGGAAGGCTGAAGATGAAATGCAGAAGTCAGCTTGGGATCAACCTTCA
  CTTCCTGAAGGAAACAAAAATAAAACCAACTTGGATGACCTAGTAAAGGGGGAAAATAGA
  TCTTCAGTTAAACACAGATTGGCAGCCATGTCTAAAGCCAGCAGAAAATTCCCAGCTAAA
  GATGTAAGCCCCAGAAGACATGTAGCTACTATCTTCCCCCAAAGTGGAAGCAGATCTGGC
  TTTGACCATTTATCTCTTGGCACAGTGGAGTGCAACCCACTGTTCCCTGAGCCTACTCCA
  AAATCTGCAGAGTCCATTGGCGAAAGCAGGTTGAGTGAGAACGGAAAGCATGTGAAGAAA
  TCCGAGAACCTTCTCCCCATTACTGTACTACCCAACAGAGAACCTTCTACACACGTCAGC
  AACCAGAAGTCTAACAGCATTTCACAACGACATCAGAATGAGTTTAAAAACGTCTCAGAA
  TCACCATCAAAGCATGAGAATTCTAAAGACGTCACAGCAGCTCAGAATTTAGTAAGAGAA
  TCAGGAGCCCCATCACCCATCACATTCACCAGCCTCAGGGAAGCAGAATTCTCTGACAAT
  CAGAGGAGGCTGAGCCCTCCTTTTCCACTGGAGCCTGCACAGAAATCTAGAGTAAGCAGT
  CCACTGGCCAGTTTTCTGCAGCAACAAAGGAGTGCTTCATCTCTGGAGTGGGAACCTGAG
  CCACACCTCTATCGTTCAAAGAGTTTAAAAAGCATTAATGTTCATGGCGATCTACTACGA
  AAAAGCCATCCTCCAAAAGTCAGGGAGCGCCATTTTTCTGAAAGCACTTCTATTGACAAT
  GCCCTGAGTCGACTGACCCTTGGGAATGAATTCTCTGTCAACAATGGGTACAGTCGAAGA
  TTCAGATCTTTTTCTGAACTCCCCTCCTGTGATGGAAATGAAAGTTGGGCTTATCGCAGC
  GGGACAAAAACAGGTCCCAGGTCTGCAATATCTATATACAGACCTATCGACTATGGGATC
  TTTGGGAAAGAACAACAGTTAGCTTTCTTAGAAAATGTAAAGAGGTCACTTACACAAGGA
  AGATTATGGAAACCAAGTTTTCTTAAGAACCCTGGCTTCCTAAAAGATGATTTGAGGAAC
  CCTCCCAACCCCTCAGAGTCATTAAGCTCAAATTCTCCCAGTAGTCAGGTGCCAGAAGAT
  GGCTTATCTCCAAGTGAACCGCTTAATATCTATGAGGATGACCCAGTGGACTCAGATTGT
  GACACAGACACAACCACAGATGATGAATACTACCTGGATGAAAATGACAAAGAGTCAGAA
  CTG
  
• Restriction Sites: Please inquire
• ACCN: NM_001144765
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001144765.1, NP_001138237.1
• RefSeq Size: 9850 bp
• RefSeq ORF: 5406 bp
• Locus ID: 23086
• Cytogenetics: 11q22.3
• Gene Summary: The protein encoded by this gene is a member of the synaptotagmin-like protein (Slp) family lacking a C2 domain. It contains an N-terminal synaptotagmin-like homology domain (SHD), and is a ras-related protein Rab-27B effector protein. This protein is thought to be involved in exosome secretion and intracellular vesicle trafficking. Reduced expression of this gene results in keratin filament defects. Mutations in this gene have been associated with some cases of epidermolysis bullosa, an inherited skin fragility disorder. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (3) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (3) with a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.