WDR79 (WRAP53) (NM_001143991) Human Untagged Clone
CAT#: SC325187
WRAP53 (untagged)-Human WD repeat containing, antisense to TP53 (WRAP53), transcript variant 3
"NM_001143991" in other vectors (4)
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | WRAP53 |
Synonyms | DKCB3; TCAB1; WDR79 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001143991, the custom clone sequence may differ by one or more nucleotides
ATGAAGACTTTGGAGACTCAACCGTTAGCTCCGGACTGCTGTCCTTCAGACCAGGACCCA GCTCCAGCCCATCCTTCTCCCCACGCTTCCCCGATGAATAAAAATGCGGACTCTGAACTG ATGCCACCGCCTCCCGAAAGGGGGGATCCGCCCCGGTTGTCCCCAGATCCTGTGGCTGGC TCAGCTGTGTCCCAGGAGCTACGGGAGGGGGACCCAGTTTCTCTCTCCACTCCCCTGGAA ACAGAGTTTGGTTCCCCTAGTGAGTTGAGTCCTCGAATCGAGGAGCAAGAACTTTCTGAA AATACAAGCCTTCCTGCAGAAGAAGCAAACGGGAGCCTTTCTGAAGAAGAAGCGAACGGG CCAGAGTTGGGGTCTGGAAAAGCCATGGAAGATACCTCTGGGGAACCCGCTGCAGAGGAC GAGGGAGACACCGCTTGGAACTACAGCTTCTCCCAGCTGCCTCGATTTCTCAGTGGTTCC TGGTCAGAGTTCAGCACCCAACCTGAGAACTTCTTGAAAGGCTGTAAGTGGGCTCCTGAC GGTTCCTGCATCTTGACCAATAGTGCTGATAACATCTTGCGAATTTATAACCTGCCCCCA GAGCTGTACCATGAGGGGGAGCAGGTGGAATATGCAGAAATGGTCCCTGTCCTTCGAATG GTGGAAGGTGATACCATCTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCA GACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTC ACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCC CATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTG CGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAA AAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTAT GCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTC GCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAAC CGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCT GGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGAT CTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGG GACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAG AAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCC GGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTT CCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGG GGGGCGCCAGACTCCAGCATCCCTGATGATCACCAGGGCGAGAAAGGGCAGGGAGGAACG GAGGGAGGTGTGGGTGAGCTGATA |
Restriction Sites | Please inquire |
ACCN | NM_001143991 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001143991.1, NP_001137463.1 |
RefSeq Size | 1847 bp |
RefSeq ORF | 1647 bp |
Locus ID | 55135 |
UniProt ID | Q9BUR4 |
Cytogenetics | 17p13.1 |
Gene Summary | This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011] Transcript Variant: This variant (3, also known as WRAP53alpha) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. |
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Product Manuals |
FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC227773 | WRAP53 (Myc-DDK-tagged)-Human WD repeat containing, antisense to TP53 (WRAP53), transcript variant 3 |
USD 510.00 |
|
RC227773L3 | Lenti-ORF clone of WRAP53 (Myc-DDK-tagged)-Human WD repeat containing, antisense to TP53 (WRAP53), transcript variant 3 |
USD 810.00 |
|
RC227773L4 | Lenti-ORF clone of WRAP53 (mGFP-tagged)-Human WD repeat containing, antisense to TP53 (WRAP53), transcript variant 3 |
USD 810.00 |
|
RG227773 | WRAP53 (tGFP-tagged) - Human WD repeat containing, antisense to TP53 (WRAP53), transcript variant 3 |
USD 710.00 |
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