ABCE1 (NM_001040876) Human Untagged Clone

CAT#: SC323716

ABCE1 (untagged)-Human ATP-binding cassette, sub-family E (OABP), member 1 (ABCE1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCE1
• Synonyms: ABC38; OABP; RLI; RLI1; RNASEL1; RNASELI; RNS4I
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001040876.1 CGCTGTGTGGCTGAAAAGTGAAGGCAAGAGCTGATTTGGCCTCTGTGCTCCCCTCCGCAA
  GGGGATCGTTTTCTCCAGAAGAGCTGGATATTCTTTCGCCCAGTTATGGCAGACAAGTTA
  ACGAGAATTGCTATTGTCAACCATGACAAATGTAAACCTAAGAAATGTCGACAGGAATGC
  AAAAAGAGTTGTCCTGTAGTTCGAATGGGAAAATTATGCATAGAGGTTACACCCCAGAGC
  AAAATAGCATGGATTTCCGAAACTCTTTGTATTGGTTGTGGTATCTGTATTAAGAAATGC
  CCCTTTGGCGCCTTATCAATTGTCAATCTACCAAGCAACTTGGAAAAAGAAACCACACAT
  CGATATTGTGCCAATGCCTTCAAACTTCACAGGTTGCCTATCCCTCGTCCAGGTGAAGTT
  TTGGGATTAGTTGGAACTAATGGTATTGGAAAGTCAACTGCTTTAAAAATTTTAGCAGGA
  AAACAAAAGCCAAACCTTGGAAAGTACGATGATCCTCCTGACTGGCAGGAGATTTTGACT
  TATTTCCGTGGATCTGAATTACAAAATTACTTTACAAAGATTCTAGAAGATGACCTAAAA
  GCCATCATCAAACCTCAATATGTAGACCAGATTCCTAAGGCTGCAAAGGGGACAGTGGGA
  TCTATTTTGGACCGAAAAGATGAAACAAAGACACAGGCAATTGTATGTCAGCAGCTTGAT
  TTAACCCACCTAAAAGAACGAAATGTTGAAGATCTTTCAGGAGGAGAGTTGCAGAGATTT
  GCTTGTGCTGTCGTTTGCATACAGAAAGCTGATATTTTCATGTTTGATGAGCCTTCTAGT
  TACCTAGATGTCAAGCAGCGTTTAAAGGCTGCTATTACTATACGATCTCTAATAAATCCA
  GATAGATATATCATTGTGGTGGAACATGATCTAAGTGTATTAGACTATCTCTCCGACTTC
  ATCTGCTGTTTATATGGTGTACCAAGCGCCTATGGAGTTGTCACTATGCCTTTTAGTGTA
  AGAGAAGGCATAAACATTTTTTTGGATGGCTATGTTCCAACAGAAAACTTGAGATTCAGA
  GATGCATCACTTGTTTTTAAAGTGGCTGAGACAGCAAATGAAGAAGAAGTTAAAAAGATG
  TGTATGTATAAATATCCAGGAATGAAGAAAAAAATGGGAGAATTTGAGCTAGCAATTGTA
  GCTGGAGAGTTTACAGATTCTGAAATTATGGTGATGCTGGGGGAAAATGGAACGGGTAAA
  ACGACATTTATCAGAATGCTTGCTGGAAGACTTAAACCTGATGAAGGAGGAGAAGTACCA
  GTTCTAAATGTCAGTTATAAGCCACAGAAAATTAGTCCCAAATCAACTGGAAGTGTTCGC
  CAGTTACTACATGAAAAGATAAGAGATGCTTATACTCACCCACAATTTGTGACCGATGTA
  ATGAAGCCTCTGCAAATTGAAAACATCATTGATCAAGAGGTGCAGACATTATCTGGTGGT
  GAACTACAGCGAGTAGCTTTAGCCCTTTGCTTGGGCAAACCTGCTGATGTCTATTTAATT
  GATGAACCATCTGCATATTTGGATTCTGAGCAAAGACTGATGGCAGCTCGAGTTGTCAAA
  CGTTTCATACTCCATGCAAAAAAGACAGCCTTTGTTGTGGAACATGACTTCATCATGGCC
  ACCTATCTAGCGGATCGCGTCATCGTTTTTGATGGTGTTCCATCTAAGAACACAGTTGCA
  AACAGTCCTCAAACCCTTTTGGCTGGCATGAATAAATTTTTGTCTCAGCTTGAAATTACA
  TTCAGAAGAGATCCAAACAACTATAGGCCACGAATAAACAAACTTAATTCAATTAAGGAT
  GTAGAACAAAAGAAGAGTGGAAACTACTTTTTCTTGGATGATTAGACTGACTCTGAGAAT
  ATTGATAAGCCATTTATTAAAAGGAGTATTTACTAGAATTTTTTGTCATATAAAACTTGA
  ATCAGGATTTTATGCCCCACATACTCTGGAACTTGAAGTATAATATACTTAATATAACAT
  AAAAAGCCAGTTGGGTTCTAAATTGTAGTTGAAACACAGAAAATGCCACTTTTCTGTTCC
  TGAAGAGGCTCTTTTGTGCATAATATTCTAAAATGAAGACATTTCAAGCTATACAAATTA
  CTTCCAAGTTTTCATGATGTATGGGAAGATTTTCAGTAGGTGTATTATATTCACGGTACC
  AAATGCTGACCAGTGTTGCTCCATTTTTTAAATCTTGAAAAGGGTTTCTGTACTTACCTG
  GTTTGCCAAGTATGCCAGTGTAATGAAACTGCCCTTATTTTAAAAGCCAGTCAAAGATTC
  CACTGATTGACATTTGATAAATAAACATCAGGATTATGTTTATTGTTTGTTTTCAGTCTT
  TGCACTATATTACCAGTATATGGTTTCCGAGGAAGATTATCTACTGCAAAACACCACTGT
  TGGAAAAATAGGTATTTTTAAATTGTTTTTAATCTTTTTTGGTGCTTTTAAACATGTTTA
  GCAAAAACCAATTCAGTTCCATTCCCCGCAAAAAACCCCTAACTTTACTCTGAACTTTTT
  TTGTTTTTGCATTCCATGAGGTTCTGTATTCAGTCATTCTCTAGGTAATGTCATTTTTGT
  ACACATATATTTATATAATCACTGATTGAGATTTAGGAAAAAGCATTTCTAAAGAATATT
  TGCTTCCCTTAGAACTACAGACTCGAAATCTTTAAAGATGGTGCCTAAGCATCTATGTAT
  TTTTTTTAAGTTCCACAGATTTTTCTGTTGGGCAGCCAAGGATTATAAACCACTTCCCTA
  AAGGCAACATTAATGCAAAAGTCCCCAGATGGCAATACAAAGTATCCCCTGGTACCACAT
  ATATTCATTTGTGAGTTTGGATATAGAGCACATTATCTAAACCATTTTGTAGTTCCAAAA
  ACCCATCTAAATTTCTTGAGTTCCTGAATTTTGAACAGGATTACCTGGAGCCTGGAGCCA
  CTTTAAGTTGTACTTCTGACTAAACTGGAATTATGAGTGAGGAAGAGTGTTTACTAAATA
  AATGACTGGGGCAAGCAAAATTGAGGAGGAAATTAGAAACTGTTTGACAAACTTTAAGAG
  CTACTTGAAATAACAGAAGTCTTGATTAATATGCAAATAATGGCTAGAAAGTATGGTTTA
  ACTGGACCCTATTATGCCTTTTAAAAATAATTTCAGTAACCCATAAATACATGTTGTAAA
  AAATTCAAATATACAGAATGGAATAAAAAAATGATCTCCCTTTATTACCCTCCCAAAGGT
  TACCAGCGTTTGAATTTAATAATGTATATTCTTTCATGCTTTTTTCTGTGCACTTACCTA
  AGTGTGAATATGTAAAGGGTTTGTTTTGTATACAAATGGGATTATACTAAAATAAGTAAT
  GCCTATTTTTAAGGATAGGTTAAATTTGTGAATGATCATTTCAAATATATTGAATAAAAT
  AAGCAAAAGCTAAAAAAAAAAAAAAAAA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_001040876
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001040876.1, NP_001035809.1
• RefSeq Size: 4191 bp
• RefSeq ORF: 1800 bp
• Locus ID: 6059
• UniProt ID: P61221
• Cytogenetics: 4q31.21
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.