LANPL (ANP32E) (NM_030920) Human Untagged Clone

CAT#: SC322183

ANP32E (untagged)-Human acidic (leucine-rich) nuclear phosphoprotein 32 family, member E (ANP32E), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LANPL
• Synonyms: LANP-L; LANPL
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322183 GTCCCAACTCTTGGACTCCATTTGCTATTCTCTTCTTTCTCCCCCACACCTATCTGGTGG
  TGGTAGTGGGCGTTTATATTTGCGTTCCTTTTCATTCATTTCTAAATCTCTTAAAAATTT
  TGGGTTGGGGGTATTGGGGAAGGCAGGAAAGGGAAAAGGAGAGTAGTAGCTGAAGAGCAA
  GAGGAGGACATGGAGATGAAGAAGAAGATTAACCTGGAGTTAAGGAACAGATCCCCGGAG
  GAGGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTG
  AATGATACTTTCAAAGAACTAGAATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTG
  GCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATATAATTTCT
  GGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGA
  AACAAAATAAAAGATCTCAGTACAGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGT
  CTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTATTTTTGAA
  CTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGAC
  TCTGAAGAGGAGGATGATGAGGATGGAGATGAAGATGATGAAGAGGAAGAGGAAAATGAA
  GCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGATGAGGAT
  GAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGC
  CTCTCATACTTAATGAAAGAAGAAATTCAGGATGAAGAAGATGATGATGACTATGTTGAA
  GAAGGGGAAGAAGAGGAAGAAGAGGAAGAAGGAGGTCTTCGAGGGGAGAAGAGGAAACGA
  GATGCTGAAGACGATGGAGAGGAAGAAGATGACTAGATCATTCTAAGACCAGATTCTCTA
  ATGTTTCTGGGTGTGCAATAGAGTGATCACATCTTTGTTTCTTCATGTACGATAGCTATC
  CCTACAGAAGATAATGTGTAACTTTTTATAGGAAAAGTGTGGTTTTACTATTTTTGCCTT
  ATCATTCCAAATAAGAACTAGTCTGTTAATGATCATATTGTATGTAGAGAAAAATTTTCA
  TTGACTCCCATTGTGGAATTCCCTAGCAATTTATTTAGACTTAATTTTTTAAATTCAAGC
  TTACTGTATTAGTCATTTTTAGCCCATAATTAAAACATGATCACTTTTAAAAAAAAAAAA
  AAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_030920
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_030920.2, NP_112182.1
• RefSeq Size: 3273 bp
• RefSeq ORF: 807 bp
• Locus ID: 81611
• UniProt ID: Q9BTT0
• Cytogenetics: 1q21.2
• Domains: LRR
• Protein Families: Druggable Genome
• Gene Summary: Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).