MSL3L1 (MSL3) (NM_078629) Human Untagged Clone

CAT#: SC322153

MSL3 (untagged)-Human male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MSL3L1
• Synonyms: MRSXBA; MRXS36; MRXSBA; MSL3L1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322153 GGCTGCCCCGGAGCCTCGCCCTCCGCCACGATGAGCAAATGAGCGCGAGCGAGGGCATGA
  AATTTAAATTCCACTCAGGGGAGAAAGTGCTGTGCTTCGAGCCTGACCCCACCAAGGCGC
  GAGTGCTGTACGATGCCAAGATTGTTGATGTTATTGTTGGGAAAGACGAAAAAGGCAGAA
  AGATCCCAGAATATCTGATCCATTTTAATGGTTGGAACAGAAGCTGGGATAGATGGGCAG
  CAGAAGATCATGTGCTTCGTGATACCGATGAAAATCGTAGATTACAGCGTAAATTGGCAA
  GAAAAGCTGTAGCTCGCCTGAGGAGCACAGGAAGAAAGAAGAAGCGCTGCAGGTTGCCTG
  GTGTGGACTCTGTCTTAAAAGGCCTCCCCACTGAAGAAAAAGATGAAAATGATGAAAACT
  CATTAAGCAGTTCCTCTGACTGTAGTGAAAACAAGGATGAAGAAATAAGTGAAGAAAGTG
  ATATTGAAGAAAAGACTGAAGTGAAAGAAGAACCAGAGCTTCAAACAAGAAGGGAAATGG
  AAGAAAGAACAATAACTATAGAAATCCCTGAAGTTCTGAAGAAGCAGCTGGAGGATGATT
  GTTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATCATAA
  CGATTTTGGAATCCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAATGAGA
  GGCCTCGTCACCATCACGTTATGCCACATGCCAACATGAACGTGCATTATATCCCAGCAG
  AAAAGAATGTTGACCTTTGTAAGGAGATGGTGGATGGATTAAGAATAACCTTTGATTACA
  CTCTCCCGTTGGTTTTACTCTATCCATATGAACAAGCTCAGTATAAAAAGGTGACTTCGT
  CTAAATTTTTTCTTCCAATTAAGGAAAGTGCCACAAGCACTAACAGGAGCCAGGAGGAAC
  TCTCTCCCAGTCCGCCTTTGTTGAATCCATCCACGCCACAGTCCACAGAGAGTCAGCCGA
  CCACCGGTGAACCAGCCACCCCCAAAAGGCGCAAAGCTGAGCCAGAAGCATTGCAGTCTC
  TGAGGCGGTCCACGCGCCACAGTGCCAACTGTGACAGGCTTTCTGAGAGCAGCGCTTCAC
  CTCAGCCCAAGCGCCGGCAGCAGGACACATCCGCCAGCATGCCCAAGCTCTTCCTGCACC
  TGGAAAAGAAGACACCTGTGCATAGCAGATCATCTTCACCTATTCCTCTGACTCCTAGCA
  AGGAAGGGAGTGCTGTGTTTGCTGGCTTTGAAGGGAGAAGAACTAATGAAATAAACGAGG
  TCCTCTCCTGGAAGCTTGTGCCTGACAATTACCCCCCAGGTGACCAGCCGCCTCCACCCT
  CTTACATTTATGGGGCACAACATTTGCTGCGATTGTTTGTGAAACTTCCAGAAATCCTTG
  GAAAGATGTCCTTTTCTGAGAAGAATCTGAAGGCTTTATTGAAGCACTTTGATCTCTTTT
  TGAGGTTTTTAGCAGAATACCACGATGACTTCTTCCCAGAGTCGGCTTATGTCGCTGCCT
  GTGAGGCACATTACAGCACCAAGAACCCCCGGGCAATTTATTAAAATGTTGTTGGTTCTG
  TAAGAGCAACTGCTCTGTCTAGTTTGGCGCTCTGGGTTCCAGGTGAATAACTAACAAGGT
  GGTGGGTCTTTACCCACAGCGCAAACACAATGCCCACCTTGGGGCTCTGTTGTTTGAGTT
  GCCCACATACTGCAGTTATTCTGTTAGGAATGATTCCCTGGGTGCCTGAAAGTGCTCTGA
  CACGACACTTGTTACTTTGCAGGCCATCTGTGATGGCAAGGAAAAAGCAACTATGTTCAC
  AGTGAAATATTCGTGGAATAGGTTAGGCCATTTCAGTAGACATTGCAGTTAGTTAGCAAG
  AACCACATTGTCTCTTTATTTGTTAGCATTAAACAAATTTTTTTTTTGCAAATTGGTTTT
  ATTTTTTTGATGAAGCCGAGCAACTCTGTCCAAAAAGGTTTAGTTTGTACTCGGAAACCA
  CAAAGTAGTCTCAAAGTATTTTAGAGGGAATCGATATTGATGGCAAAAGAAAATTTGCAG
  CTATGCATTTGCTTCTAACGGTTCCCTCTCTGTGAAACATTATTTTTGGTGATCTAAAGA
  AAGCATTGCCTTTCTTATTTGAGATTTTACAGCTATACTTTGTTGTGTAATGTTATGGTT
  CCCTTTCTGTAAAATGTTATTTTTGGTGATCTAAATAAAGCCTGTCTTGTTTGAAAGAAA
  AAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_078629
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_078629.1, NP_523353.1
• RefSeq Size: 2343 bp
• RefSeq ORF: 1566 bp
• Locus ID: 10943
• UniProt ID: Q8N5Y2
• Cytogenetics: Xp22.2
• Domains: CHROMO
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
  Transcript Variant: This variant (1) encodes the longest isoform (a).