FRMD5 (NM_032892) Human Untagged Clone

CAT#: SC317977

FRMD5 (untagged)-Human FERM domain containing 5 (FRMD5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FRMD5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032892, the custom clone sequence may differ by one or more nucleotides
  ATGCTGAGCAGGTTGATGAGCGGCAGCAGCAGGAGCCTGGAGCGCGAGTACAGCTGCACC
  GTGCGGCTGCTGGACGACAGCGAGTACACCTGCACCATCCAGAGAGATGCCAAAGGCCAG
  TACCTGTTTGACCTTCTTTGCCACCATCTGAACCTACTTGAGAAAGACTATTTTGGTATC
  CGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAAAGTCTGTGGTGAAA
  CAATTGAGATCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGAC
  CCTGCTGCTCTGAAAGAAGAAATAACCAGGTATTTAGTCTTCCTGCAGATCAAAAGGGAT
  CTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTGTTAGCAGCTTACATC
  CTTCAAGCGGAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAG
  TTCCAGTTTTTCCCTAAACATTCAGAGAAGCTGGAAAGGAAAATTGCTGAGATTCACAAG
  ACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTCTTAAGAAAAGCACAG
  ACATTGGAAACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCA
  TTTCTGGCCTTCACTCCTTTTGGGTTTGTTGTTCTTCAAGGAAACAAGAGGGTCCACTTC
  ATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACTTTCTATTTATACGTA
  AGTCAGAAAGAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGT
  AAGCACCTCTGGAAATGTGGAATCGAGAACCAAGCCTTCTACAAGCTGGAGAAGTCAAGC
  CAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGCCGGTTCCGATACAGT
  GGCCGAGTTGCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAA
  ATACACAGAGCAGGGATGGTTCCCAGCCGGAGCTGTCCCTCCATAACCCATGGCCCAAGG
  CTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCCATCATGGAAGGCCTA
  GAGTCCTTACGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACC
  TTCCTGCCTCACGTGAGAAGCAGCCGGACAGATAGCAATGAGCGAGTAGCTGTGATTGCA
  GACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTGGCTGAGCACAGCCTG
  GAGCTGATGTTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAG
  GAATCTGAAGCCAGCACCCCAACTGCTACAGAGGTGGAGGCCCTTGGGGGAGAGCTGAGG
  GCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGGTGAATAAGTTTGTTCTAAGT
  GTCCTCCGTTTGCTCCTTGTGACCATGGGACTCCTCTTTGTTTTGCTCCTCCTCCTGATC
  ATCCTTACCGAGTCTGACCTTGACATTGCCTTTTTCCGTGATATCCGCCAGACCCCCGAG
  TTTGAACAATTCCACTATCAATACTTTTGTCCCCTCAGGCGATGGTTTGCCTGCAAAATC
  CGCTCAGTGGTGAGCCTGCTCATTGACACC
  
• Restriction Sites: Please inquire
• ACCN: NM_032892
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_032892.3, NP_116281.2
• RefSeq Size: 2261 bp
• RefSeq ORF: 1713 bp
• Locus ID: 84978
• UniProt ID: Q7Z6J6
• Cytogenetics: 15q15.3
• Protein Families: Transmembrane
• Gene Summary: May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675). May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) encodes the longest isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.