Exosome Component 9 (EXOSC9) (NM_005033) Human Untagged Clone

CAT#: SC317720

EXOSC9 (untagged)-Human exosome component 9 (EXOSC9), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXOSC9
• Synonyms: p5; p6; PCH1D; PM/Scl-75; PMSCL1; RRP45; Rrp45p
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005033, the custom clone sequence may differ by one or more nucleotides
  ATGAAGGAAACGCCACTCTCAAACTGCGAACGCCGCTTCCTACTCCGTGCCATCGAAGAG
  AAGAAGCGGCTGGATGGCAGACAAACCTATGATTATAGGAACATCAGGATCTCATTTGGA
  ACAGATTACGGATGCTGCATTGTGGAACTTGGAAAAACAAGAGTTCTTGGACAGGTTTCC
  TGTGAACTTGTGTCTCCAAAACTCAATCGGGCAACAGAAGGTATTCTTTTTTTTAACCTT
  GAACTCTCTCAGATGGCCGCTCCAGCTTTCGAACCTGGCAGGCAGTCAGATCTCTTGGTG
  AAGTTGAATCGACTCATGGAAAGATGTCTAAGAAATTCGAAGTGTATAGACACTGAGTCT
  CTCTGTGTTGTTGCTGGTGAAAAGGTTTGGCAAATACGTGTAGACCTACATTTATTAAAT
  CATGATGGAAATATTATTGATGCTGCCAGCATTGCTGCAATCGTGGCCTTATGTCATTTC
  CGAAGACCTGATGTCTCTGTCCAAGGAGATGAAGTAACACTGTATACACCTGAAGAGCGT
  GATCCTGTACCATTAAGTATCCACCACATGCCCATTTGTGTCAGTTTTGCCTTTTTCCAG
  CAAGGAACATATTTATTGGTGGATCCCAATGAACGAGAAGAACGTGTGATGGATGGCTTG
  CTGGTGATTGCCATGAACAAACATCGAGAGATTTGTACTATCCAGTCCAGTGGTGGGATA
  ATGCTACTAAAAGATCAAGTTCTGAGATGCAGTAAAATCGCTGGTGTGAAAGTAGCAGAA
  ATTACAGAGCTAATATTGAAAGCTTTGGAGAATGACCAAAAAGTAAGGAAAGAAGGTGGA
  AAGTTTGGTTTTGCAGAGTCTATAGCAAATCAAAGGATCACAGCATTTAAAATGGAAAAG
  GCCCCTATTGATACCTCGGATGTAGAAGAAAAAGCAGAAGAAATCATTGCTGAAGCAGAA
  CCTCCTTCAGAAGTTGTTTCTACACCTGTGCTATGGACTCCTGGAACTGCCCAAATTGGA
  GAGGGAGTAGAAAACTCCTGGGGTGATCTTGAAGACTCTGAGAAGGAAGATGATGAAGGC
  GGTGGTGATCAAGCTATCATTCTTGATGGTATAAAAATGGACACTGGAGTAGAAGTCTCT
  GATATTGGAAGCCAAGATGCTCCCATAATACTCTCAGATAGTGAAGAAGAAGAAATGATC
  ATTTTGGAACCAGACAAGAATCCAAAGAAAATAAGAACACAGACCACCAGTGCAAAACAA
  GAAAAAGCACCAAGTAAAAAGCCAGTGAAAAGAAGAAAAAAGAAGAGAGCTGCCAAT
  
• Restriction Sites: Please inquire
• ACCN: NM_005033
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005033.2, NP_005024.2
• RefSeq Size: 1593 bp
• RefSeq ORF: 1320 bp
• Locus ID: 5393
• UniProt ID: Q06265
• Cytogenetics: 4q27
• Domains: RNase_PH_C
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: RNA degradation
• Gene Summary: This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.