TM6SF2 (NM_001001524) Human Untagged Clone

CAT#: SC317603

TM6SF2 (untagged)-Human transmembrane 6 superfamily member 2 (TM6SF2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TM6SF2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001001524 edited
  ATGGACATCCCGCCGCTGGCCGGCAAGATCGCGGCGCTGTCGCTGAGCGCCCTCCCGGTG
  TCCTACGCGCTCAACCACGTCTCGGCGCTCTCGCACCCCCTGTGGGTGGCATTGATGAGC
  GCCCTAATCCTGGGTCTGCTTTTCGTGGCGGTCTACAGCTTGTCCCATGGCGAGGTCTCC
  TATGACCCACTCTATGCTGTCTTCGCTGTCTTCGCCTTCACCTCGGTTGTGGACCTCATC
  ATCGCTCTTCAGGAAGACAGCTATGTGGTGGGCTTCATGGAGTTCTACACCAAGGAGGGA
  GAGCCATACCTGCGCACAGCGCACGGAGTCTTCATCTGCTACTGGGATGGCACTGTTCAC
  TACCTCCTCTACCTGGCCATGGCCGGCGCCATCTGCAGAAGGAAGAGATACCGGAATTTT
  GGACTCTACTGGCTGGGTTCCTTCGCCATGAGCATCCTGGTGTTCCTTACAGGAAACATT
  CTTGGCAAATACAGCTCCGAGATCAGGCCTGCCTTCTTCCTCACCATCCCCTACCTGCTG
  GTGCCATGCTGGGCTGGCATGAAGGTCTTCAGCCAGCCCCGGGCGCTAACCCGCTGCACC
  GCCAACATGGTGCAAGAGGAACAAAGAAAGGGACTCCTGCAGCGTCCGGCTGACCTGGCC
  CTTGTCATATATCTCATCCTTGCTGGCTTCTTCACTCTGTTCCGGGGCCTGGTGGTGCTT
  GATTGCCCCACAGATGCCTGCTTTGTCTATATCTACCAGTATGAGCCATACCTGCGGGAC
  CCTGTGGCCTACCCTAAGGTGCAGATGCTGATGTACATGTTTTATGTCCTGCCTTTCTGC
  GGCCTGGCTGCCTATGCTCTCACCTTCCCTGGTTGCTCCTGGCTTCCAGACTGGGCCTTG
  GTGTTTGCTGGAGGCATCGGCCAGGCACAGTTCTCGCACATGGGGGCTTCCATGCACCTG
  CGCACACCCTTCACCTACCGTGTGCCTGAGGACACCTGGGGCTGCTTCTTCGTGTGCAAT
  CTGCTGTATGCGCTGGGCCCCCACCTGCTGGCCTACCGTTGCCTTCAGTGGCCCGCATTC
  TTCCACCAGCCACCACCCTCCGACCCCCTAGCCCTCCACAAGAAGCAGCATTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001001524
• Insert Size: 1100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001001524.2, NP_001001524.2
• RefSeq Size: 1483 bp
• RefSeq ORF: 1134 bp
• Locus ID: 53345
• UniProt ID: Q9BZW4
• Cytogenetics: 19p13.11
• Protein Families: Transmembrane
• Gene Summary: Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content (PubMed:24531328, PubMed:24927523). May function as sterol isomerase (PubMed:25566323).[UniProtKB/Swiss-Prot Function]