BAT3 (BAG6) (NM_001098534) Human Untagged Clone

CAT#: SC316443

BAG6 (untagged)-Human BCL2-associated athanogene 6 (BAG6), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BAG6
• Synonyms: BAG-6; BAT3; D6S52E; G3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC316443 representing NM_001098534.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGAGCCTAATGATAGTACCAGTACCGCTGTGGAGGAGCCTGACAGCTTGGAGGTGTTGGTGAAGACC
  TTGGACTCTCAAACTCGTACCTTTATTGTGGGGGCCCAGATGAATGTAAAAGAGTTTAAGGAGCACATT
  GCTGCCTCTGTCAGCATCCCATCTGAAAAACAACGGCTCATTTACCAGGGACGAGTTCTGCAAGATGAT
  AAGAAGCTTCAGGAATACAATGTTGGGGGAAAGGTTATCCACCTGGTGGAACGGGCTCCTCCTCAGACT
  CACCTCCCTTCTGGGGCATCTTCTGGGACGGGGTCTGCCTCAGCCACTCATGGTGGGGGATCCCCCCCT
  GGTACTCGGGGGCCTGGGGCCTCTGTTCATGACCGGAATGCCAACAGCTATGTCATGGTTGGAACCTTC
  AATCTTCCTAGTGACGGCTCTGCTGTGGATGTTCACATCAACATGGAACAGGCCCCGATTCAGAGTGAG
  CCCCGGGTACGGCTGGTGATGGCTCAGCACATGATCAGGGATATACAGACCTTACTATCCCGGATGGAG
  TGTCGAGGAGGGCCCCAACCGCAGCACAGTCAGCCGCCCCCGCAGCCACCGGCTGTGACCCCGGAGCCA
  GTAGCCTTGAGCTCTCAAACATCAGAACCAGTTGAAAGTGAAGCACCTCCCCGGGAGCCCATGGAGGCA
  GAAGAAGTGGAGGAGCGTGCCCCAGCCCAGAACCCGGAGCTCACTCCTGGCCCAGCCCCAGCGGGCCCA
  ACACCTGCCCCGGAAACAAATGCACCCAACCATCCTTCCCCTGCGGAGTATGTCGAGGTGCTCCAGGAG
  CTACAGCGGCTGGAGAGTCGCCTCCAGCCCTTCTTGCAGCGCTACTACGAGGTTCTGGGTGCTGCTGCC
  ACCACGGACTACAATAACAATCACGAGGGCCGGGAGGAGGATCAGCGGTTGATCAACTTGGTAGGGGAG
  AGCCTGCGACTGCTGGGCAACACCTTTGTTGCACTGTCTGACCTGCGCTGCAATCTGGCCTGCACGCCC
  CCACGACACCTGCATGTGGTCCGGCCTATGTCTCACTACACCACCCCCATGGTGCTCCAGCAGGCAGCC
  ATTCCCATACAGATCAATGTGGGAACCACTGTGACCATGACAGGAAATGGGACTCGGCCCCCCCCAACT
  CCCAATGCAGAGGCACCTCCCCCTGGTCCTGGGCAGGCCTCATCCGTGGCTCCGTCTTCTACCAATGTC
  GAGTCCTCAGCTGAGGGGGCTCCCCCGCCAGGTCCAGCTCCCCCGCCAGCCACCAGCCACCCGAGGGTC
  ATCCGGATTTCCCACCAGAGTGTGGAACCCGTGGTCATGATGCACATGAACATTCAAGATTCTGGCACA
  CAGCCTGGTGGTGTTCCGAGTGCTCCCACTGGCCCCCTGGGACCCCCTGGTCATGGCCAAACCCTGGGA
  CAGCAGGTGCCAGGCTTCCCAACAGCTCCAACCCGGGTGGTGATTGCCCGGCCCACTCCTCCACAGGCT
  CGGCCTTCCCATCCTGGAGGGCCCCCAGTCTCTGGGACACTGCAGGGCGCCGGTCTGGGTACCAATGCC
  TCGTTGGCCCAGATGGTGAGCGGCCTTGTGGGGCAGCTTCTTATGCAGCCAGTCCTTGTGGCTCAGGGG
  ACCCCAGGTATGGCTCCACCGCCAGCCCCTGCCACTGCTTCTGCCAGTGCTGGCACCACCAACACAGCT
  ACCACAGCTGGCCCCGCTCCTGGGGGGCCTGCCCAGCCTCCACCCACCCCTCAACCCTCCATGGCTGAT
  CTTCAGTTCTCTCAGCTTCTGGGGAACCTGCTAGGGCCTGCAGGGCCAGGGGCTGGAGGGTCTGGTGTG
  GCTTCTCCCACCATCACTGTGGCGATGCCTGGTGTCCCTGCCTTTCTCCAAGGCATGACTGACTTCTTG
  CAGGCAACACAGACAGCCCCTCCACCACCCCCACCTCCTCCACCCCCACCACCTGCCCCAGAGCAGCAG
  ACCATGCCCCCACCAGGCTCCCCTTCTGGTGGCGCAGGGAGTCCTGGAGGCCTGGGTCTTGAGAGCCTG
  TCACCGGAGTTTTTTACCTCAGTGGTGCAGGGTGTGCTCAGCTCCCTGCTGGGCTCCCTGGGGGCTCGG
  GCTGGCAGCAGTGAAAGTATTGCTGCCTTCATACAACGCCTCAGTGGATCCAGCAACATCTTTGAGCCT
  GGAGCTGATGGGGCCCTTGGATTCTTTGGGGCCTTGCTTTCTCTTCTGTGCCAGAACTTCTCTATGGTG
  GACGTAGTGATGCTTCTCCATGGGCATTTCCAGCCACTACAACGGCTCCAGCCCCAGCTGCGATCCTTC
  TTCCACCAGCACTACCTGGGTGGTCAGGAGCCCACACCCAGTAACATCCGGATGGCAACCCACACATTG
  ATCACGGGGCTAGAAGAGTATGTGCGGGAGAGTTTTTCCTTGGTGCAGGTTCAGCCAGGTGTGGACATC
  ATCCGGACAAACCTGGAATTTCTCCAAGAGCAGTTTAATAGCATTGCTGCGCATGTGCTGCATTGCACA
  GATAGTGGATTTGGGGCCCGGTTGCTGGAGTTGTGTAACCAAGGCCTGTTTGAATGCCTGGCCCTAAAC
  CTGCACTGCTTGGGGGGACAGCAGATGGAGCTTGCTGCTGTTATCAATGGCCGAATTCGTCGTATGTCT
  CGTGGGGTGAATCCCTCCTTGGTGAGCTGGCTGACCACTATGATGGGACTGAGGCTTCAGGTGGTACTG
  GAGCACATGCCTGTAGGCCCTGATGCCATTCTCAGATACGTTCGCAGGGTTGGTGATCCCCCCCAGCCA
  CTTCCTGAGGAGCCAATGGAAGTTCAGGGAGCAGAAAGAGCTTCCCCTGAGCCTCAGCGGGAGAATGCT
  TCCCCAGCCCCTGGAACAACAGCAGAAGAGGCCATGTCCCGAGGTCCACCTCCTGCTCCTGAGGGGGGC
  TCCCGGGATGAACAGGATGGAGCTTCAGCTGAGACAGAACCTTGGGCAGCTGCAGTCCCCCCAGAATGG
  GTCCCTATTATCCAGCAGGACATTCAGAGCCAGCGGAAGGTGAAACCGCAGCCCCCTCTGAGTGATGCC
  TACCTCAGTGGTATGCCTGCCAAGAGACGCAAGACGATGCAGGGTGAGGGCCCCCAGCTGCTTCTCTCA
  GAGGCTGTGAGCCGGGCAGCTAAGGCAGCCGGAGCTCGGCCCCTGACGAGCCCCGAGAGCCTGAGCCGG
  GACCTGGAGGCACCAGAGGTTCAGGAGAGCTACAGGCAGCAGCTCCGGTCTGATATACAAAAACGACTG
  CAGGAAGACCCCAACTACAGTCCCCAGCGCTTCCCCAATGCCCAGCGGGCCTTTGCTGATGATCCTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001098534
• Insert Size: 3381 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001098534.1
• RefSeq Size: 3660 bp
• RefSeq ORF: 3381 bp
• Locus ID: 7917
• UniProt ID: P46379
• Cytogenetics: 6p21.33
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 118.7 kDa
• Gene Summary: This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) differs in the 5' UTR and utilizes an alternative in-frame splice site in the 5' coding region, compared to variant 1. Variants 2, 3, and 4 encode the same isoform (b), which is 6 aa shorter than isoform a.