BANK1 (NM_001083907) Human Untagged Clone

CAT#: SC316069

BANK1 (untagged)-Human B-cell scaffold protein with ankyrin repeats 1 (BANK1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BANK1
• Synonyms: BANK
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001083907, the custom clone sequence may differ by one or more nucleotides
  ATGATATATGAAGAAGATGCTGAGGAATGGGCTCTGTACTTGACAGAAGTATTTTTACAT
  GTTGTGAAAAGGGAAGCCATCCTGTTATATCGCTTGGAGAATTTCTCTTTTCGGCATTTG
  GAGTTGCTGAACTTAACGTCTTACAAATGTAAACTTTTGATATTATCAAATAGCCTGCTT
  AGAGACCTAACTCCAAAGAAATGTCAGTTTCTGGAAAAGATACTTCATTCACCAAAAAGT
  GTAGTTACTTTGCTTTGTGGAGTGAAGAGTTCAGATCAGCTCTATGAATTACTAAATATC
  TCTCAAAGCAGATGGGAGATCTCAACTGAACAGGAACCTGAAGACTACATCTCTGTAATC
  CAGAGTATCATATTCAAAGATTCTGAAGACTACTTTGAGGTCAACATTCCAACAGACCTA
  CGAGCAAAACATTCTGGGGAAATAAGTGAGAGAAAGGAAATTGAAGAACTATCAGAAGCT
  TCAAGAAACACCATACCACTAGCAGTGGTGCTTCCCACTGAAATTCCATGTGAGAATCCT
  GGTGAAATATTCATAATTTTGAGAGATGAAGTAATTGGTGATACTGTAGAGGTTGAATTT
  ACATCAAGTAATAAGCGCATTAGAACACGGCCAGCCCTTTGGAATAAGAAAGTCTGGTGC
  ATGAAAGCTTTAGAGTTTCCTGCTGGTTCAGTCCATGTCAATGTCTACTGTGATGGAATC
  GTTAAAGCTACAACCAAAATTAAGTACTACCCAACAGCAAAGGCAAAGGAATGCCTATTC
  AGAATGGCAGATTCAGGAGAGAGTTTGTGCCAGAATAGCATTGAAGAACTTGATGGTGTC
  CTTACATCCATATTCAAACATGAGATACCATATTATGAGTTCCAGTCTCTTCAAACTGAA
  ATTTGTTCTCAAAACAAATATACTCATTTCAAAGAACTTCCAACTCTTCTCCACTGTGCA
  GCAAAATTTGGCTTAAAGAACCTGGCTATTCATTTGCTTCAATGTTCAGGAGCAACCTGG
  GCATCTAAGATGAAAAATATGGAGGGTTCAGACCCCGCACATATTGCTGAAAGGCATGGT
  CACAAAGAACTCAAGAAAATCTTCGAAGACTTTTCAATCCAAGAAATTGACATAAATAAT
  GAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACA
  CAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCT
  GAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACAC
  AGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTC
  ATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCT
  CTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTA
  CCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTT
  AGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAG
  CAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATATGACATG
  ATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGA
  CCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTAC
  ATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGT
  GGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTCTACTCTCAGG
  GGCTGTCTAACTGATGGTCAGGAAGAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGG
  AAAATGTCTATGGATGAAGCTCTGGAGAAATTTAAACACTGGCAGATGGGAAAAAGTGGC
  CTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTATTGGGAAAAGG
  CCAGAAGAAGAAAATGTCTATAATAAACTCACCATTGTGCACCATCCAGGTGGTAAGGAA
  ACTGCCCACAATGAAAATAAGTTTTATAATGTACACTTCAGCAATAAGCTTCCTGCTCGA
  CCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCAT
  
• Restriction Sites: Please inquire
• ACCN: NM_001083907
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001083907.1, NP_001077376.1
• RefSeq Size: 3224 bp
• RefSeq ORF: 2268 bp
• Locus ID: 55024
• UniProt ID: Q8NDB2
• Cytogenetics: 4q24
• Gene Summary: The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (2) uses an alternate exon at its 5' end, compared to variant 1, which produces a unique 5' UTR and causes translation initiation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1.