PTOP (ACD) (NM_001082487) Human Untagged Clone
CAT#: SC316006
ACD (untagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3
"NM_001082487" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | PTOP |
Synonyms | PIP1; PTOP; TINT1; TPP1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC316006 representing NM_001082487.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCCTGGCCGCTGTCAGAGTGACGCCGCGATGAGAGTAAACGGGCCAGCATCCCGTGCACCAGCGGGG TGGACCAGCGGGAGTCTGCACACAGGCCCCCGAGCAGGACGCCCTCGTGCGCAGGCGCGGGGTGTACGT GGGCGGGGCCTCCTCCTCCGGCCCCGCCCAGCGAAGGAGCTTCCTCTTCCGAGGAAAGGCGGGGCCTGG GCGCCCGCGGGAAACCCGGGCCCGTTGCATCCGCTGGGTGTAGCCGTGGGGATGGCAGGTTCGGGGAGG CTGGTCCTACGGCCCTGGATTCGGGAGCTGATTCTGGGGTCAGAGACACCCTCCAGTCCACGAGCCGGG CAGCTGCTTGAGGACGCCGAGGCCGCGGTCGCGGGCCCATCCCACGCCCCTGATACGTCCGACGTCGGG GCCACGCTGCTTGTGTCTGACGGGACCCACAGTGTCCGATGCCTGGTGACGCGGGAGGCCCTGGACACC TCGGACTGGGAGGAGAAGGAGTTCGGCTTCCGCGGGACAGAGGGCCGGCTGCTGCTGCTGCAGGACTGC GGGGTTCATGTCCAGGTCGCTGAGGGCGGCGCGCCCGCAGAGTTCTATCTCCAGGTGGACCGCTTCAGC CTGCTGCCCACGGAGCAGCCCCGGCTACGGGTGCCTGGTTGCAACCAAGACTTAGATGTTCAGAAAAAG CTCTATGACTGCCTTGAGGAGCACCTTTCAGAGTCCACCTCGTCCAATGCAGGCCTATCACTGTCCCAG CTTCTGGATGAAATGCGGGAGGACCAGGAGCATCAGGGGGCACTCGTGTGCCTGGCTGAAAGCTGCCTG ACACTGGAGGGCCCTTGCACAGCACCCCCTGTCACCCACTGGGCTGCCTCACGATGCAAGGCCACGGGA GAAGCTGTGTACACTGTCCCCAGCTCAATGCTGTGCATCTCTGAGAATGACCAGCTAATTCTGAGCTCT CTAGGCCCCTGTCAGAGGACACAGGGCCCTGAGCTGCCCCCACCAGACCCGGCTCTGCAGGACCTATCT CTGACCCTCATAGCCTCTCCTCCTTCCTCACCCAGTTCCTCAGGAACCCCGGCCTTACCCGGCCACATG TCATCCGAGGAAAGTGGTACCAGCATCAGCCTTCTGCCTGCCCTGTCCTTGGCTGCTCCAGACCCAGGG CAGAGAAGCAGCTCCCAGCCCTCACCAGCCATCTGCTCAGCCCCTGCCACCCTGACCCCCAGGTCCCCA CACGCCAGCCGTACCCCCAGCTCCCCACTCCAGAGCTGCACTCCCAGTCTCTCACCCCGTAGCCATGTC CCCAGTCCACACCAGGCTCTTGTGACCAGGCCCCAGAAACCTAGCCTGGAGTTCAAGGAGTTTGTAGGG TTGCCCTGCAAGAATCGGCCGCCTTTTCCCAGGACCGGAGCTACCAGGGGAGCCCAGGAGCCCTGCTCT GTCTGGTATGAGTATGAGCCACCCTGCACGTCCCTCTGTGCTCGGGTCCAAGCTGTCAGGCTTCCTCCC CAGCTCATGGCCTGGGCCTTGCACTTTCTGATGGATGCACAGCCAGGGTCTGAGCCAACTCCGATGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001082487 |
Insert Size | 1587 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001082487.1 |
RefSeq Size | 2047 bp |
RefSeq ORF | 1587 bp |
Locus ID | 65057 |
UniProt ID | Q96AP0 |
Cytogenetics | 16q22.1 |
MW | 55.9 kDa |
Gene Summary | This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) uses alternate in-frame splice sites in the 5' and 3' coding regions, compared to variant 1, resulting in a shorter protein (isoform 3). |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC212674 | ACD (Myc-DDK-tagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3 |
USD 737.00 |
|
RC212674L1 | Lenti-ORF clone of ACD (Myc-DDK-tagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3 |
USD 1,037.00 |
|
RC212674L2 | Lenti-ORF clone of ACD (mGFP-tagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3 |
USD 1,037.00 |
|
RC212674L3 | Lenti-ORF clone of ACD (Myc-DDK-tagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3 |
USD 1,037.00 |
|
RC212674L4 | Lenti-ORF clone of ACD (mGFP-tagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3 |
USD 1,037.00 |
|
RG212674 | ACD (tGFP-tagged) - Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3 |
USD 937.00 |
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