FRMD5 (AK090572) Human Untagged Clone

CAT#: SC313981

(untagged)-Human cDNA FLJ33253 fis, clone ASTRO2005343, weakly similar to BAND 4.1-LIKE PROTEIN 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FRMD5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK090572, the custom clone sequence may differ by one or more nucleotides
  ATGCTGAGCAGGTTGATGAGCGGCAGCAGCAGGAGCCTGGAGCGCGAGTACAGCTGCACC
  GTGCGGCTGCTGGACGACAGCGAGTACACCTGCACCATCCAGAGAGATGCCAAAGGCCAG
  TACCTGTTTGACCTTCTTTGCCACCATCTGAACCTACTTGAGAAAGACTATTTTGGTATC
  CGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAAAGTCTGTGGTGAAG
  TTTTATCCTGCAGACCCTGCTGCTCTGAAAGAAGAAATAACCAGGTATTTAGTCTTCCTG
  CAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTG
  TTAGCAGCTTACATCCTTCAAGCGGAGATTGGGGATTATGACTCAGGGAAACACCCTGAA
  GGCTACAGCTCCAAGTTCCAGTTTTTCCCTAAACATTCAGAGAAGCTGGAAAGGAAAATT
  GCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTC
  TTAAGAAAAGCACAGACATTGGAAACATATGGAGTGGATCCTCACCCATGTAAGGACGTG
  TCAGGAAATGCTGCATTTCTGGCCTTCACTCCTTTTGGGTTTGTTGTTCTTCAAGGAAAC
  AAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACT
  TTCTATTTATACGTAAGTCAGAAAGAGGAAAAGAAAATTATTCTTACATATTTTGCTCCA
  ACTCCTGAAGCGTGTAAGCACCTCTGGAAATGTGGAATCGAGAACCAAGCCTTCTACAAG
  CTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGC
  CGGTTCCGATACAGTGGCCGAGTTGCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAA
  CGGGAGCCACCGGAAATACACAGAGCAGGGATGGTTCCCAGCCGGAGCTGTCCCTCCATA
  ACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCC
  ATCATGGAAGGCCTAGAGTCCTTACGGGACAGTGCCCATTCCACACCAGTGCGTTCCACT
  TCCCATGGGGACACCTTCCTGCCTCACGTGAGAAGCAGCCGGACAGATAGCAATGAGCGA
  GTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTG
  GCTGAGCACAGCCTGGAGCTGATGTTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGC
  ATTGAGGAGGAGAAGGAATCTGAAGCCAGCACCCCAACTGCTACAGAGGTGGAGGCCCTT
  GGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGGTGAAT
  AAGTTTGTTCTAAGTGTCCTCCGTTTGCTCCTTGTGACCATGGGACTCCTCTTTGTTTTG
  CTCCTCCTCCTGATCATCCTTACCGAGTCTGACCTTGACATTGCCTTTTTCCGTGATATC
  CGCCAGACCCCCGAGTTTGAACAATTCCACTATCAATACTTTTGTCCCCTCAGGCGATGG
  TTTGCCTGCAAAATCCGCTCAGTGGTGAGCCTGCTCATTGACACC
  
• Restriction Sites: Please inquire
• ACCN: AK090572
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AK090572.1, BAC03480.1
• RefSeq Size: 2493 bp
• RefSeq ORF: 1668 bp
• Locus ID: 84978
• Cytogenetics: 15q15.3
• Protein Families: Transmembrane
• Gene Summary: May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675). May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).[UniProtKB/Swiss-Prot Function]