Neurotensin Receptor 1 (NTSR1) (NM_002531) Human Untagged Clone

CAT#: SC313374

NTSR1 (untagged)-Human neurotensin receptor 1 (high affinity) (NTSR1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Neurotensin Receptor 1
• Synonyms: NTR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002531 edited
  ATGCGCCTCAACAGCTCCGCGCCGGGAACCCCGGGCACGCCGGCCGCCGACCCCTTCCAG
  CGGGCGCAGGCCGGACTGGAGGAGGCGCTGCTGGCCCCGGGCTTCGGCAACGCTTCGGGC
  AACGCGTCGGAGCGCGTCCTGGCGGCACCCAGCAGCGAGCTGGACGTGAACACCGACATC
  TACTCCAAAGTGCTGGTGACCGCCGTGTACCTGGCGCTCTTCGTGGTGGGCACGGTGGGC
  AACACGGTGACGGCGTTCACGCTGGCGCGGAAGAAGTCGCTGCAGAGCCTGCAGAGCACG
  GTGCATTACCACCTGGGCAGCCTGGCGCTGTCCGACCTGCTCACCCTGCTGCTGGCCATG
  CCCGTGGAGCTGTACAACTTCATCTGGGTGCACCACCCCTGGGCCTTCGGCGACGCCGGC
  TGCCGCGGCTACTACTTCCTGCGCGACGCCTGCACCTACGCCACGGCCCTCAACGTGGCC
  AGCCTGAGTGTGGAGCGCTACCTGGCCATCTGCCACCCCTTCAAGGCCAAGACCCTCATG
  TCCCGAAGCCGCACCAAGAAGTTCATCAGCGCCATCTGGCTCGCCTCGGCCCTGCTGGCG
  GTGCCTATGCTGTTCACCATGGGCGAGCAGAACCGCAGCGCCGACGGCCAGCACGCCGGC
  GGCCTGGTGTGCACCCCCACCATCCACACTGCCACCGTCAAGGTCGTCATACAGGTCAAC
  ACCTTCATGTCCTTCATATTCCCCATGGTGGTCATCTCGGTCCTGAACACCATCATCGCC
  AACAAGCTGACCGTCATGGTACGCCAGGCGGCCGAGCAGGGCCAAGTGTGCACGGTCGGG
  GGCGAGCACAGCACATTCAGCATGGCCATCGAGCCTGGCAGGGTCCAGGCCCTGCGGCAC
  GGCGTGCGCGTCCTACGTGCAGTGGTCATCGCCTTTGTGGTCTGCTGGCTGCCCTACCAC
  GTGCGGCGCCTCATGTTCTGCTACATCTCGGATGAGCAGTGGACTCCGTTCCTCTATGAC
  TTCTACCACTACTTCTACATGGTGACCAACGCACTCTTCTACGTCAGCTCCACCATCAAC
  CCCATCCTGTACAACCTCGTCTCTGCCAACTTCCGCCACATCTTCCTGGCCACACTGGCC
  TGCCTCTGCCCGGTGTGGCGGCGCAGGAGGAAGAGGCCAGCCTTCTCGAGGAAGGCCGAC
  AGCGTGTCCAGCAACCACACCCTCTCCAGCAATGCCACCCGCGAGACGCTGTACTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_002531
• Insert Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone has been fully sequenced and found one SNP within the protein associated with this reference, NM_002531.1.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002531.1, NP_002522.1
• RefSeq Size: 4131 bp
• RefSeq ORF: 1257 bp
• Locus ID: 4923
• UniProt ID: P30989
• Cytogenetics: 20q13.33
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008]