ARMC5 (NM_024742) Human Untagged Clone

CAT#: SC309244

ARMC5 (untagged)-Human armadillo repeat containing 5 (ARMC5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARMC5
• Synonyms: AIMAH2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC309244 representing NM_024742.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCGGCTGCGAAGCCAACCCTCACGGACTCGCTCTCGTTCTGCCTCGCGCAGCTCGCGGCGGCGGCC
  GGGGAGGCTCTGGGTGGGGAAAAGGACCCAGCGACCAACGAGACACCCCTGAGCCGCGCGCTCCTAGCC
  CTCCGCACGCGCCACATCAAGGCAGCGGGGGGAATCGAGCGCTTCCGGGCACGCGGCGGGCTCCGCCCC
  CTACTCGCGCTGCTACGGCGAGCGGCTGCAGCGGGTTCCGCCCCGTCCCAGGCAGGCCCCGGCTCCGCC
  CCCTCGTCGGCCGCGTCGGGAGCTTCTAGCCCCGCCCCCGCGTCGGGCCCCGCCCCCTCCGCTGTGTCG
  TCGTCTAGTCCTACGCCGCCAGTGCGCCTGCGCAAGACGCTGGACTTGGCGCTCAGCATCCTAGCCGAT
  TGCTGTACGGAAGGGGCGTGCCGGACCGAAGTGCGCAGACTCGGAGGCATACTCCCTTTGGTGACCATT
  CTTCAGTGCATGAAGACAGACAGCATCCAGAACCGAACGGCCCGTGCCCTGGGGAACTTAGCCATGGAA
  CCTGAGAGCTGTGGGGACATCCACTGTGCTGGTGCTGTTCCCCTGCTTGTGGAGAGCCTGACAGCCTGC
  CAGGACTCGCAGTGCCTACAGAGCGTGGTGCGTGCCCTCCGTAACCTGGCAGACTCACCCCAGCACCGC
  CTGGCCTTGGCACAGCAGGGAGCAGTGCGTCCGCTGGCCGAGCTCCTGGCCACTGCCCCAGATGCTGCA
  CTGACCTTAGCCCTCGTCCGTGCCCTCCTGGAACTCAGCCGAGGCTGCTCCCGGGCCTGTGCTGAGCAG
  CTAAGTCTGGGTGGGGGATTGGGCCCACTCGTCAGCCTGGCTTCCCACCCCAAGCGGGCAGTACGCGAG
  GGAACCATTCTGATCCTCGCCAACCTGTGTGCCCAGGGCCTGATTCGGCCTGCACTGGGCAATGCTGGT
  GGCGTGGAGGTGCTGGTAGATGAGCTCCGGCAGCGCCGGGATCCTAATGGAGCTAGCCCAACCTCCCAG
  CAGCCCCTGGTGCGGGCTGTGTGCCTCCTATGTCGTGAGGCCATCAACCGGGCCCGACTGCGGGATGCT
  GGTGGCTTGGATCTACTGATGGGCCTGCTGCGGGACCCTCGTGCAAGCGCATGGCACCCTCGTATTGTG
  GCTGCCCTTGTGGGGTTTCTGTATGACACTGGGGCCCTGGGCCGGCTGCAGGCTCTGGGACTTGTGCCT
  CTCCTGGCTGGGCAGCTGTGTGGTGAGGCTGGTGAGGAGGAAGAAGAGGGAAGAGAAGCTGCTTCCTGG
  GACTTTCCTGAGGAGAGGACCCCTGAGCGGGCACAGGGTGGAAGCTTCCGGAGCCTCAGGTCGTGGCTG
  ATCTCCGAGGGCTATGCCACAGGCCCTGATGACATCTCCCCCGACTGGTCTCCTGAGCAGTGTCCGCCG
  GAGCCCATGGAGCCGGCCAGCCCCGCCCCGACCCCGACCTCGCTGCGGGCACCACGCACCCAACGCACT
  CCGGGCCGCAGCCCCGCCGCCGCCATCGAGGAGCCTTGGGGACGCGAAGGGCCAGCCCTGCTGCTGCTG
  TCGCGCTTTTCCCAGGCCCCTGACCCAAGTGGGGCACTTGTGACCGGCCCGGCGCTGTACGGCCTGCTG
  ACCTATGTGACCGGCGCACCGGGCCCGCCCAGCCCACGTGCACTGCGCATTCTGTCACGCCTCACCTGC
  AACCCTGCCTGCCTCGAGGCCTTCGTGCGCAGCTATGGCGCGGCGCTGCTGCGGGCCTGGCTGGTGCTG
  GGGGTGGCGCCTGACGATTGGCCGGCACCACGTGCCCGGCCCACTCTCCACAGCCGGCACCGAGAGCTG
  GGTGAGTTCCCATACCCACCCGTCTCCTTGCCCCCATGTGAGTCCCCATCCTCCCCCATGGCTTCCATG
  GGCCCAGAACCTCACCTTCCCACTCACCTGTCCTCCCCAGCCCGTCCTCCAGACAACCTGTCACCAGAG
  TGGGGTGGGGAGCAGGGCGTTCCAGTCCCTCCATGGGCCCACAGGCAGAGTTCTGCTGTGTCCTCTGCC
  CTAGCCCTGGGACCCAGATACCCTAACTCTAGATGCAGCCCCGCGCCCAGGATCTGGGCTGGTCTGTGC
  TTCTTTCCTGGCTCTGCCATTGGTTCAGCACTGTCCTGA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_024742
• Insert Size: 2178 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_024742.2
• RefSeq Size: 4707 bp
• RefSeq ORF: 2178 bp
• Locus ID: 79798
• UniProt ID: Q96C12
• Cytogenetics: 16p11.2
• MW: 75.6 kDa
• Gene Summary: This gene encodes a member of the ARM (armadillo/beta-catenin-like repeat) superfamily. The ARM repeat is a tandemly repeated sequence motif with approximately 40 amino acid long. This repeat is implicated in mediating protein-protein interactions. The encoded protein contains seven ARM repeats. Mutations in this gene are associated with primary bilateral macronodular adrenal hyperplasia, which is also known as ACTH-independent macronodular adrenal hyperplasia 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
  Transcript Variant: This variant (2) differs in the 5' and 3' UTRs and has multiple coding region differences, compared to variant 3. These differences cause translation initiation at a downstream AUG and a different 3' coding sequence. The resulting isoform (b) has a shorter N-terminus and a distinct C-terminus, compared to isoform c.