Archaemetzincin 2 (AMZ2) (NM_001033572) Human Untagged Clone

CAT#: SC302740

AMZ2 (untagged)-Human archaelysin family metallopeptidase 2 (AMZ2), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AMZ2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001033572, the custom clone sequence may differ by one or more nucleotides
  ATGCAAATAATACGGCACTCCGAACAGACACTAAAAACAGCTCTCATCTCAAAGAACCCA
  GTGCTTGTATCACAGTATGAGAAATTAAATGCTGGGGAACAACGTTTAATGAATGAAGCC
  TTCCAGCCAGCCAGTGATCTCTTTGGACCCATTACCTTGCATTCTCCATCAGATTGGATC
  ACCTCCCACCCTGAGGCTCCCCAAGACTTTGAACAGTTCTTCAGTGATCCTTACAGAAAG
  ACACCCTCTCCAAACAAACGCAGCATTTATATACAGTCCATTGGCTCTCTAGGAAACACC
  AGAATTATCAGTGAAGAATATATTAAATGGCTCACGGGCTACTGTAAAGCATATTTCTAT
  GGCTTGAGAGTAAAACTCCTAGAACCAGTTCCTGTTTCTGTAACAAGATGTTCCTTTAGA
  GTCAATGAGAACACACACAACCTACAAATTCATGCAGGGGACATCCTGAAGTTCTTGAAA
  AAGAAGAAACCTGAAGATGCCTTCTGTGTTGTGGGAATAACAATGATTGATCTTTACCCA
  AGAGACTCGTGGAATTTTGTCTTTGGACAGGCCTCTTTGACAGATGGTGTGGGGATATTC
  AGCTTTGCCAGGTATGGCAGTGATTTTTATAGCATGCACTATAAAGGCAAAGTGAAGAAG
  CTCAAGAAAACATCTTCAAGTGACTATTCAATTTTCGACAACTATTATATTCCAGAAATA
  ACTAGTGTTTTACTACTTCGATCCTGTAAGACTTTAACCCATGAGATCGGACACATATTT
  GGACTGCGACACTGCCAGTGGCTTGCATGCCTCATGCAAGGCTCCAACCACTTGGAAGAA
  GCTGACCGGCGCCCTCTAAACCTTTGCCCTATCTGTTTGCACAAGTTGCAGTGTGCTGTT
  GGCTTCAGCATTGTAGAAAGATACAAAGCACTGGTGAGGTGGATTGATGATGAATCTTCT
  GACACACCTGGAGCAACTCCAGAACACAGTCACGAGGATAATGGGAATTTACCGAAACCC
  GTGGAAGCCTTTAAGGAATGGAAAGAGTGGATAATAAAATGCCTGGCTGTTCTCCAAAAA
  TGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001033572
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001033572.1, NP_001028744.1
• RefSeq Size: 1395 bp
• RefSeq ORF: 1083 bp
• Locus ID: 51321
• UniProt ID: Q86W34
• Cytogenetics: 17q24.2
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]
  Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-5 and 7-17 all encode the same isoform (1).